-DNA prep refs
-Genotyping refs
-Mouse tail refs
-Buffer and Reagent refs
-Transgenic refs
-Yolk sac refs




  • Severe neuronal losses with age in the parietal cortex and ventrobasal thalamus of mice transgenic for the human NF-L neurofilament protein.
  • Response of glia, mast cells and the blood brain barrier, in transgenic mice expressing interleukin-3 in astrocytes, an experimental model for CNS demyelination.
  • Overexpression of glycine-extended gastrin in transgenic mice results in increased colonic proliferation.
  • Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development.
  • Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia.
  • Thermogenic activity of growth hormone transgenic mice.
  • Differences in amyloid deposition in islets of transgenic mice expressing human islet amyloid polypeptide versus human islets implanted into nude mice.
  • Direct regulatory interaction of the eyeless protein with an eye-specific enhancer in the sine oculis gene during eye induction in Drosophila.
  • Extended duration of DH-JH rearrangement in immunoglobulin heavy chain transgenic mice: implications for regulation of allelic exclusion.
  • Role of a single aquaporin isoform in root water uptake.
  • The role of microglial cells and astrocytes in fibrillar plaque evolution in transgenic APP(SW) mice.
  • Identification of the deoxyribonucleic acid-binding site of a regulatory protein involved in prostate-specific and androgen receptor-dependent gene expression.
  • Role of brain-derived neurotrophic factor in target invasion in the gustatory system.
  • Species-specific alternative splicing of transgenic RNA in the mammary glands of pigs, rabbits, and mice.
  • The insulin-like growth factor axis and prostate cancer: lessons from the transgenic adenocarcinoma of mouse prostate (TRAMP) model.
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  • Cell-surface expression and alloantigenic function of a human nonclassical class I molecule (HLA-E) in transgenic mice.
  • Expansion of extrathymic T cells as well as granulocytes in the liver and other organs of granulocyte-colony stimulating factor transgenic mice: why they lost the ability of hybrid resistance.
  • In vivo replication of recombinant murine cytomegalovirus driven by the paralogous major immediate-early promoter-enhancer of human cytomegalovirus.
  • Differential impact of T cell repertoire diversity in diabetes-prone or -resistant IL-10 transgenic mice.
  • High resolution MRI and MRS: a feasibility study for the investigation of focal cerebral ischemia in mice.
  • Organic acid metabolism in plants: from adaptive physiology to transgenic varieties for cultivation in extreme soils.
  • From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins.
  • CpG-oligodeoxynucleotides co-stimulate primary T cells in the absence of antigen-presenting cells.
  • Cytokine regulation of mucus production in a model of allergic asthma.
  • Differential induction of adhesion molecule and chemokine expression by LTalpha3 and LTalphabeta in inflammation elucidates potential mechanisms of mesenteric and peripheral lymph node development.
  • Antibodies to human ZP3 induce reversible contraception in transgenic mice with 'humanized' zonae pellucidae.
  • Costimulation reverses the defect in IL-2 but not effector cytokine production by T cells with impaired IkappaBalpha degradation.
  • Adoptive immunotherapy prevents prostate cancer in a transgenic animal model.
  • Antigen-specific T cell activation and proliferation during oral tolerance induction.
  • Watching a synapse grow: noninvasive confocal imaging of synaptic growth in Drosophila.
  • Ozone-induced cell death occurs via two distinct mechanisms in Arabidopsis: the role of salicylic acid.
  • Transgenic crop plants expressing synthetic cry9Aa gene are protected against insect damage.
  • Prolongation of the effective duration of cytomedical therapy by re-injecting SK2 hybridoma cells microencapsulated within alginate-poly(L)lysine-alginate membranes into human interleukin-6 transgenic mice.
  • Retinoid kinetics in eye tissues of VPP transgenic mice and their normal littermates.
  • Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model.
  • Tracking an embryonic L1 retrotransposition event.
  • Preneoplastic mammary tumor markers: Cripto and Amphiregulin are overexpressed in hyperplastic stages of tumor progression in transgenic mice.
  • RESPONSIVE-TO-ANTAGONIST1, a Menkes/Wilson disease-related copper transporter, is required for ethylene signaling in Arabidopsis.
  • Tissue-specific transcriptional activity of a pancreatic islet cell-specific enhancer sequence/Pax6-binding site determined in normal adult tissues in vivo using transgenic mice.
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  • Role of the Trichoderma harzianum endochitinase gene, ech42, in mycoparasitism.
  • Measurement of DNA damage and repair in the lambda LIZ transgene in a Big Blue rat cell line by quantitative PCR.
  • Lung-specific mutagenicity and mutational spectrum in B6C3F1 lacI transgenic mice following inhalation exposure to 1,2-epoxybutene.
  • Human nerve growth factor beta (hNGF-beta): mammary gland specific expression and production in transgenic rabbits.
  • Localization and expression of integrin subunits in the embryoid bodies of F9 teratocarcinoma cells.
  • Seed yield and plant biomass increases in rice are conferred by deregulation of endosperm ADP-glucose pyrophosphorylase.
  • Use of an internal ribosome entry site for bicistronic expression of Cre recombinase or rtTA transactivator.
  • Overexpression of heme oxygenase-1 is neuroprotective in a model of permanent middle cerebral artery occlusion in transgenic mice.
  • Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor.
  • Mode of action considerations in the use of transgenic animals for mutagenicity and carcinogenicity evaluations.
  • Stable transformation of Toxoplasma gondii based on a pyrimethamine resistant trifunctional dihydrofolate reductase-cytosine deaminase-thymidylate synthase gene that confers sensitivity to 5-fluorocytosine.
  • TEL/PDGFbetaR induces hematologic malignancies in mice that respond to a specific tyrosine kinase inhibitor.
  • Variable immune response against a developmentally regulated self-antigen.
  • A gain-of-function mutation in the sodium channel gene Scn2a results in seizures and behavioral abnormalities.
  • Papers to appear in forthcoming issues
  • Processing of preproricin in transgenic tobacco.
  • Mechanism of hexosamine-induced insulin resistance in transgenic mice overexpressing glutamine:fructose-6-phosphate amidotransferase: decreased glucose transporter GLUT4 translocation and reversal by treatment with thiazolidinedione.
  • Surfactant protein B inhibits endotoxin-induced lung inflammation.
  • Production of low-lactose milk by ectopic expression of intestinal lactase in the mouse mammary gland.
  • The 5'-flanking region of the mouse adenylyl cyclase type VIII gene imparts tissue-specific expression in transgenic mice.
  • Formal analysis of electrogenic sodium, potassium, chloride and bicarbonate transport in mouse colon epithelium.
  • Conservation of the expression and function of apterous orthologs in Drosophila and mammals.
  • Recombinant growth differentiation factor-9 (GDF-9) enhances growth and differentiation of cultured early ovarian follicles.
  • Regulation of Hoxa2 in cranial neural crest cells involves members of the AP-2 family.
  • Molecular control of transgene escape from genetically modified plants.
  • Characterization of mechanical withdrawal responses and effects of mu-, delta- and kappa-opioid agonists in normal and mu-opioid receptor knockout mice.
  • Genomic structure and chromosomal localization of the mouse persyn gene.
  • Myocardial dysfunction and male mortality in peroxisome proliferator-activated receptor alpha knockout mice overexpressing lipoprotein lipase in muscle.
  • Development and function of autospecific dual TCR+ T lymphocytes.
  • A vascular bed-specific pathway.
  • Consequences of overexpression of growth hormone in transgenic mice on liver cytochrome P450 enzymes.
  • Human invariant V alpha 24-J alpha Q TCR supports the development of CD1d-dependent NK1.1+ and NK1.1- T cells in transgenic mice.
  • Position-independent and copy-number-related expression of a goat bacterial artificial chromosome alpha-lactalbumin gene in transgenic mice.
  • Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production.
  • Transgenic interleukin 10 prevents induction of experimental autoimmune encephalomyelitis.
  • Mice transgenic for intracellular interleukin-1 receptor antagonist type 1 are protected from collagen-induced arthritis.
  • The human T cell leukemia virus type I-tax gene is responsible for the development of both inflammatory polyarthropathy resembling rheumatoid arthritis and noninflammatory ankylotic arthropathy in transgenic mice.
  • High resistance and control of biological risks in transgenic plants expressing modified plum pox virus coat protein.
  • Use of log-linear analysis to construct explanatory models for TDBP- and AFB1-induced mutation spectra in lacI transgenic animals.
  • Elicitor-responsive promoter regions in the tryptophan decarboxylase gene from Catharanthus roseus.
  • Absence of internal ribosome entry site-mediated tissue specificity in the translation of a bicistronic transgene.
  • Overexpression of BiP in tobacco alleviates endoplasmic reticulum stress.
  • Molecular and cytogenetic characterization of a transgene locus that induces silencing and methylation of homologous promoters in trans.
  • T-cell receptor transgenic analysis of tumor-specific CD8 and CD4 responses in the eradication of solid tumors.
  • Acute-phase responses in transgenic mice with CNS overexpression of IL-1 receptor antagonist.
  • Expression of the apolipoprotein E gene in the skin is controlled by a unique downstream enhancer.
  • Nicotianamine synthase gene expression differs in barley and rice under Fe-deficient conditions.
  • Loss of cortical and thalamic neuronal tenascin-C expression in a transgenic mouse expressing exon 1 of the human Huntington disease gene.
  • Conditional expression of a dominant-negative c-Myb in vascular smooth muscle cells inhibits arterial remodeling after injury.
  • Human BRCA1 gene rescues the embryonic lethality of Brca1 mutant mice.
  • In vivo studies of the gamma subunit of retinal cGMP-phophodiesterase with a substitution of tyrosine-84.
  • Lipid hydroperoxides in plants.
  • Transgenic oil palm: production and projection.
  • Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality.
  • Induction of pre-B cell proliferation after de novo synthesis of the pre-B cell receptor.
  • Plant salt tolerance.
  • Polyomavirus large T-antigen protects mouse cells from Fas-, TNF-alpha- and taxol-induced apoptosis.
  • Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle.
  • Overexpression of the CT GalNAc transferase inhibits muscular dystrophy in a cleavage-resistant dystroglycan mutant mouse.
  • Expression and stable germline transmission of neomycin-resistance gene in transgenic mice.
  • Overexpression of cardiac I-kappaBalpha prevents endotoxin-induced myocardial dysfunction.
  • Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain.
  • Clinical aspects and perspectives in islet xenotransplantation.
  • Control of hair growth and follicle size by VEGF-mediated angiogenesis.
  • Macromolecular trafficking between Nicotiana tabacum and the holoparasite Cuscuta reflexa.
  • Visualization of fibrillar amyloid deposits in living, transgenic Caenorhabditis elegans animals using the sensitive amyloid dye, X-34.
  • Signaling pathways regulating the expression of proteases during tumor progression
  • Assembly of functional alpha6beta3gamma2delta GABA(A) receptors in vitro.
  • Regulation of vasoactive intestinal peptide receptor expression in developing nervous systems.
  • Adrenal tumorigenesis targeted by the corticotropin-regulated promoter of the aldo-keto reductase AKR1B7 gene in transgenic mice.
  • Postnatal overexpression of insulin-like growth factor II in transgenic mice is associated with adrenocortical hyperplasia and enhanced steroidogenesis.
  • Expression of a constitutively active Stat6 in vivo alters lymphocyte homeostasis with distinct effects in T and B cells.
  • Salicylic acid induces the expression of a number of receptor-like kinase genes in Arabidopsis thaliana.
  • Fungal pathogen protection in potato by expression of a plant defensin peptide.
  • Short-term infection with Helicobacter pylori and 1 week exposure to metronidazole does not enhance gastric mutation frequency in transgenic mice.
  • Insulin-like growth factor-I (IGF-I) protects myelination from undernutritional insult: studies of transgenic mice overexpressing IGF-I in brain.
  • Cre recombinase expression in cerebellar Purkinje cells.
  • Antibody phage display applications for nuclear medicine imaging and therapy.
  • Co-localization of multiple antigens and specific DNA. A novel method using methyl methacrylate-embedded semithin serial sections and catalyzed reporter deposition.
  • Cbfa1 contributes to the osteoblast-specific expression of type I collagen genes.
  • Expression of N-myc and MRP genes and their relationship to N-myc gene dosage and tumor formation in a murine neuroblastoma model.
  • Impairments in learning and memory accompanied by neurodegeneration in mice transgenic for the carboxyl-terminus of the amyloid precursor protein.
  • Transgenic studies of fatty acid oxidation gene expression in nonobese diabetic mice.
  • Generation of transgenic rats with YACs and BACs: preparation procedures and integrity of microinjected DNA.
  • Genetic and pharmacological demonstration of differential recruitment of cAMP-dependent protein kinases by synaptic activity.
  • Suppressive role of endogenous regucalcin in the enhancement of nitric oxide synthase activity in liver cytosol of normal and regucalcin transgenic rats.
  • Quantitative histological analysis of amyloid deposition in Alzheimer's double transgenic mouse brain.
  • Identification of ligands and coligands for the ecdysone-regulated gene switch.
  • Differential effects of diethylstilbestrol and 2,3,7,8-tetrachlorodibenzo-p-dioxin on thymocyte differentiation, proliferation, and apoptosis in bcl-2 transgenic mouse fetal thymus organ culture.
  • Assembly of double-shelled, virus-like particles in transgenic rice plants expressing two major structural proteins of rice dwarf virus.
  • Expression of cyclooxygenase mRNA in the livers of mice with interferon-gamma chronic hepatitis.
  • Oral immunogenicity of the plant derived spike protein from swine-transmissible gastroenteritis coronavirus.
  • Temporal and spatial control of the Sycp1 gene transcription in the mouse meiosis: regulatory elements active in the male are not sufficient for expression in the female gonad.
  • Modular long-range regulation of Myf5 reveals unexpected heterogeneity between skeletal muscles in the mouse embryo.
  • Expression of antisense hsp70 is a major determining factor in heat-induced cell death of P-19 carcinoma cells.
  • Increased Fecal Bile Acid Excretion in Transgenic Mice With Elevated Expression of Human Phospholipid Transfer Protein.
  • DeltaFosB-induced cataract.
  • Genetic manipulation of isoflavone 7-O-methyltransferase enhances biosynthesis of 4'-O-methylated isoflavonoid phytoalexins and disease resistance in alfalfa.
  • Catecholamines are required for the acquisition of secretory responsiveness by sweat glands.
  • Interleukin-4 transgenic mice develop glomerulosclerosis independent of immunoglobulin deposition.
  • Motor neuron cell death in a mouse model of FALS is not mediated by the p53 cell survival regulator.
  • Dissecting megakaryocytopoiesis in vivo with toxigenes.
  • Complement is activated in kidney by endotoxin but does not cause the ensuing acute renal failure.
  • Reduced blood pressure and increased sensitivity of the vasculature to parathyroid hormone-related protein (PTHrP) in transgenic mice overexpressing the PTH/PTHrP receptor in vascular smooth muscle.
  • Detection of PACH1, a nuclear factor implicated in the transcriptional regulation of meiotic and early haploid stages of spermatogenesis.
  • Pituitary adenylate cyclase-activating polypeptide precursor is processed solely by prohormone convertase 4 in the gonads.
  • Local production of anti-CD4 antibody by transgenic allogeneic grafts affords partial protection.
  • The effect of Gi-protein inactivation on basal, and beta(1)- and beta(2)AR-stimulated contraction of myocytes from transgenic mice overexpressing the beta(2)-adrenoceptor.
  • Interferon gamma signaling alters the function of T helper type 1 cells.
  • MAP kinase kinase 6-p38 MAP kinase signaling cascade regulates cyclooxygenase-2 expression in cardiac myocytes in vitro and in vivo.
  • Differential effects of dystrophin and utrophin gene transfer in immunocompetent muscular dystrophy (mdx) mice.
  • Transgene repeats in aspen: molecular characterisation suggests simultaneous integration of independent T-DNAs into receptive hotspots in the host genome.
  • Retinoblastoma gene promoter directs transgene expression exclusively to the nervous system.
  • Unravelling the net ? cytokines and diseases
  • Chronic modulation of the TCR repertoire in the lymphoid periphery.
  • Impaired neurotransmitter systems by Abeta amyloidosis in APPsw transgenic mice overexpressing amyloid beta protein precursor.
  • HCV-core protein accelerates recovery from the insensitivity of liver cells to Fas-mediated apoptosis induced by an injection of anti-Fas antibody in mice.
  • Temporally controlled somatic mutagenesis in smooth muscle.
  • Enhancement of chemical hepatocarcinogenesis by the HIV-1 tat gene.
  • Cell death after exposure to subarachnoid hemolysate correlates inversely with expression of CuZn-superoxide dismutase.
  • Molecular cloning and developmental expression of AtGR1, a new growth-related Arabidopsis gene strongly induced by ionizing radiation.
  • New cytokinin metabolites in IPT transgenic Arabidopsis thaliana plants.
  • Increased susceptibility to ischemia-induced brain damage in transgenic mice overexpressing a dominant negative form of SHP2.
  • Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis.
  • Comparison of growth and fatty acid metabolism in rats fed diets containing equal levels of gamma-linolenic acid from high gamma-linolenic acid canola oil or borage oil.
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  • cis- and trans-Acting determinants for translation of psbD mRNA in Chlamydomonas reinhardtii.
  • Nitric oxide prevents cardiovascular disease and determines survival in polyglobulic mice overexpressing erythropoietin.
  • Essential role of caffeoyl coenzyme A O-methyltransferase in lignin biosynthesis in woody poplar plants.
  • Ubiquitous overexpression of a transgene encoding the extracellular portion of the Drosophila roughest-irregular chiasm C protein induces early embryonic lethality.
  • Transformation of Stomoxys calcitrans with a Hermes gene vector.
  • Cytokinin and gibberellin activate SaMADS A, a gene apparently involved in regulation of the floral transition in Sinapis alba.
  • Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice.
  • Effect of overexpression of human apo A-I in C57BL/6 and C57BL/6 apo E-deficient mice on 2 lipoprotein-associated enzymes, platelet-activating factor acetylhydrolase and paraoxonase. Comparison of adenovirus-mediated human apo A-I gene transfer and human apo A-I transgenesis.
  • A murine monoclonal antibody produced in transgenic plants with plant-specific glycans is not immunogenic in mice.
  • Telomere attrition and Chk2 activation in human heart failure.
  • Adenylylcyclase increases responsiveness to catecholamine stimulation in transgenic mice.
  • Progressive segregation of unmyelinated axons in peripheral nerves, myelin alterations in the CNS, and cyst formation in the kidneys of myelin and lymphocyte protein-overexpressing mice.
  • Levels of dna damage are unaltered in mice overexpressing human catalase in nuclei.
  • CD4 help-independent induction of cytotoxic CD8 cells to allogeneic P815 tumor cells is absolutely dependent on costimulation.
  • Proteotyping of mammary tissue from transgenic and gene knockout mice with immunohistochemical markers: a tool to define developmental lesions.
  • V gamma 1+ T cells suppress and V gamma 4+ T cells promote susceptibility to coxsackievirus B3-induced myocarditis in mice.
  • Differential mutation of transgenic and endogenous loci in vivo.
  • Detection of mutations in transgenic fish carrying a bacteriophage lambda cII transgene target.
  • Development of spontaneous arthritis in beta2-microglobulin-deficient mice without expression of HLA-B27: association with deficiency of endogenous major histocompatibility complex class I expression.
  • Parathyroid xenotransplantation without immunosuppression in experimental hypoparathyroidism: long-term in vivo function following microencapsulation with a clinically suitable alginate.
  • Metabolic pathway engineering in cotton: Biosynthesis of polyhydroxybutyrate in fiber cells.
  • Analysis of alternative transcripts of the flax L6 rust resistance gene.
  • Suppressive role of endogenous regucalcin in the regulation of nitric oxide synthase activity in heart muscle cytosol of normal and regucalcin transgenic rats.
  • Characterization of the transposition pattern of the Ac element in Arabidopsis thaliana using endonuclease I-SceI.
  • Distribution of K5, K10 in transgenic mouse with lac Z reporter gene
  • Specific mutations induced by triplex-forming oligonucleotides in mice.
  • High-resolution localization of Drosophila Spt5 and Spt6 at heat shock genes in vivo: roles in promoter proximal pausing and transcription elongation.
  • Fumonisin B1-induced cell death in arabidopsis protoplasts requires jasmonate-, ethylene-, and salicylate-dependent signaling pathways.
  • Periodic triggering of an inducible gene for control of a wild population.
  • Prevention of HER-2/neu transgenic mammary carcinoma by tamoxifen plus interleukin 12.
  • A second T-region of the soybean-supervirulent chrysopine-type Ti plasmid pTiChry5, and construction of a fully disarmed vir helper plasmid.
  • Life-supporting human complement regulator decay accelerating factor transgenic pig liver xenograft maintains the metabolic function and coagulation in the nonhuman primate for up to 8 days.
  • MRI/MRS assessment of in vivo murine cardiac metabolism, morphology, and function at physiological heart rates.
  • Ontogeny of T cell tolerance to peripherally expressed antigens.
  • Mouse inducible costimulatory molecule (ICOS) expression is enhanced by CD28 costimulation and regulates differentiation of CD4+ T cells.
  • Role of SCL/Tal-1, GATA, and ets transcription factor binding sites for the regulation of flk-1 expression during murine vascular development.
  • Genetic mosaic analysis based on Cre recombinase and navigated laser capture microdissection.
  • A study of transgenic IFV cattle integrated with human serum albumin gene
  • A duodenum-specific enhancer regulates expression along three axes in the small intestine.
  • Increased leakiness of the tetracycline-inducible Triple-Op promoter in dividing cells renders it unsuitable for high inducible levels of a dominant negative CDC2aAt gene.
  • Role of the amino-terminal domain of simian virus 40 early region in inducing tumors in secretin-expressing cells in transgenic mice.
  • Upregulation of HSP27 in a transgenic model of ALS.
  • Transgenic expression of cecropin B, an antibacterial peptide from Bombyx mori, confers enhanced resistance to bacterial leaf blight in rice.
  • Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression.
  • Impact of genetic manipulation on the fitness of Anopheles stephensi mosquitoes.
  • Group-II phospholipase A(2) enhances oxidized low density lipoprotein-induced macrophage growth through enhancement of GM-CSF release.
  • The characterization of differential calcium signalling in tobacco guard cells.
  • Tegument-specific, virus-reactive CD4 T cells localize to the cornea in herpes simplex virus interstitial keratitis in humans.
  • Induction of tolerance to immunogenic tumor antigens associated with lymphomagenesis in HOX11 transgenic mice.
  • Overexpression of heat shock protein 70 in R6/2 Huntington's disease mice has only modest effects on disease progression.
  • Induction of antitumor immunity by vaccination of dendritic cells transfected with MUC1 RNA.
  • Technical advance: An estrogen receptor-based transactivator XVE mediates highly inducible gene expression in transgenic plants.
  • Suppressor T cells regulate the nonanergic cell population that remains after peripheral tolerance is induced to the Mls-1 antigen in T cell receptor Vbeta 8.1 transgenic mice.
  • Transgenic plants expressing cationic peptide chimeras exhibit broad-spectrum resistance to phytopathogens.
  • Expression of Ly49A on T cells alters the threshold for T cell responses.
  • Experimental induction of retinal ganglion cell death in adult mice.
  • A novel brain receptor is expressed in a distinct population of olfactory sensory neurons.
  • Elevated levels of intrachromosomal homologous recombination in Arabidopsis overexpressing the MIM gene.
  • Erythroid overexpression of C/EBPgamma in transgenic mice affects gamma-globin expression and fetal liver erythropoiesis.
  • Context-dependent EKLF responsiveness defines the developmental specificity of the human epsilon-globin gene in erythroid cells of YAC transgenic mice.
  • Growth factors regulate expression of mineral associated genes in cementoblasts.
  • Regeneration of transgenic skeletal muscles with altered timing of expression of the basic helix-loop-helix muscle regulatory factor MRF4.
  • Accelerated growth of hepatocytes in association with Up-regulation of cyclin E in transgenic mice expressing the dominant negative form of retinoic acid receptor.
  • Astrocytic alterations in interleukin-6/Soluble interleukin-6 receptor alpha double-transgenic mice.
  • Functional properties of skeletal muscle from transgenic animals with upregulated heat shock protein 70.
  • Temporal and spatial activity of a promoter from a pea enzyme inhibitor gene and its exploitation for seed quality improvement.
  • Macrophage-targeted CTP:phosphocholine cytidylyltransferase (1-314) transgenic mice.
  • Magnetic resonance microscopy of mouse embryos in utero.
  • IFN-gamma overexpression within the pancreas is not sufficient to rescue Pax4, Pax6, and Pdx-1 mutant mice from death.
  • A GATA-dependent right ventricular enhancer controls dHAND transcription in the developing heart.
  • Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes.
  • Mammary gland tumor in transgenic mice expressing targeted beta-casein/HPV16E6 fusion gene.
  • Mechanisms of vascular instability in a transgenic mouse model of sickle cell disease.
  • Local and systemic induction of two defense-related subtilisin-like protease promoters in transgenic Arabidopsis plants. Luciferin induction of PR gene expression.
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  • Delayed rejection of fetal pig pancreas in CD4 cell deficient mice was correlated with residual helper activity.
  • "Gene-swap knock-in" cassette in mice to study allelic differences in human genes.
  • DOH1, a class 1 knox gene, is required for maintenance of the basic plant architecture and floral transition in orchid.
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  • The broad bean nodulin VfENOD18 is a member of a novel family of plant proteins with homologies to the bacterial MJ0577 superfamily.
  • Regulation of peripheral lymph node genesis by the tumor necrosis factor family member TRANCE.
  • Stimulating effect of HIV-1 coat protein gp120 on corticotropin-releasing hormone and arginine vasopressin in the rat hypothalamus: involvement of nitric oxide.
  • Microbial lipopeptides induce the production of IL-17 in Th cells.
  • The quantity of TCR signal determines positive selection and lineage commitment of T cells.
  • Quantification of p53 expression in the nervous system.
  • Isolation of the regulatory regions and genomic organization of the porcine alpha1,3-galactosyltransferase gene.
  • Embryonic stem cells and transgenic mice ubiquitously expressing a tau-tagged green fluorescent protein.
  • Hepatocarcinogen quinoline induces G:C to C:G transversions in the cII gene in the liver of lambda/lacZ transgenic mice (MutaMouse).
  • Multiple transcriptional domains, with distinct left and right components, in the atrial chambers of the developing heart.
  • Genes encoding nitrilase-like proteins from tobacco.
  • Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development.
  • Ligand-dependent genetic recombination in fibroblasts : a potentially powerful technique for investigating gene function in fibrosis.
  • Lactational performance of first-parity transgenic gilts expressing bovine alpha-lactalbumin in their milk.
  • alpha-Adrenergic response and myofilament activity in mouse hearts lacking PKC phosphorylation sites on cardiac TnI.
  • Production of transgenic chimera rabbit fetuses using somatic cell nuclear transfer.
  • Different regulatory sequences are required for parvalbumin gene expression in skeletal muscles and neuronal cells of transgenic mice.
  • Harlequin (hlq) and short blue root (sbr), two Arabidopsis mutants that ectopically express an abscisic acid- and auxin-inducible transgenic carrot promoter and have pleiotropic effects on morphogenesis.
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  • Agrobacterium tumefaciens-mediated transformation of maize embryos using a standard binary vector system.
  • Transgenically ectopic expression of Bmp4 to the Msx1 mutant dental mesenchyme restores downstream gene expression but represses Shh and Bmp2 in the enamel knot of wild type tooth germ.
  • An in vitro model of neurotrauma in organotypic spinal cord cultures from adult mice.
  • Genome-wide identification of tissue-specific enhancers in the Ciona tadpole.
  • Differential effects of angiotensin II and angiotensin-(1-7) at the nucleus tractus solitarii of transgenic rats with low brain angiotensinogen.
  • Characterization of germination-specific lipid transfer proteins from Euphorbia lagascae.
  • Studies on DNA-protein interactions in the HS3 of the human beta-LCR
  • Overexpression of apolipoprotein B in the heart impedes cardiac triglyceride accumulation and development of cardiac dysfunction in diabetic mice.
  • Disruption of inducible nitric oxide synthase improves beta-adrenergic inotropic responsiveness but not the survival of mice with cytokine-induced cardiomyopathy.
  • Antisense expression of carnation cDNA encoding ACC synthase or ACC oxidase enhances polyamine content and abiotic stress tolerance in transgenic tobacco plants.
  • Lack of ductal development in the absence of functional estrogen receptor alpha delays mammary tumor formation induced by transgenic expression of ErbB2/neu.
  • Caspase cascades in human immunodeficiency virus-associated neurodegeneration.
  • Characterization of an iron-dependent regulatory sequence involved in the transcriptional control of AtFer1 and ZmFer1 plant ferritin genes by iron.
  • Altered neuronal nitric oxide synthase expression contributes to disease progression in Huntington's disease transgenic mice.
  • Apoptosis of autoreactive CD8 lymphocytes as a potential mechanism for the abrogation of type 1 diabetes by islet-specific TNF-alpha expression at a time when the autoimmune process is already ongoing.
  • Inducible and brain region-specific CREB transgenic mice.
  • PYY-Tag transgenic mice displaying abnormal (H+-K+)ATPase activity and gastric mucosal barrier impairment.
  • Peptide antigen priming of naive, but not memory, CD8 T cells requires a third signal that can be provided by IL-12.
  • Regulatory effects of novel neurotrophin-1/b cell-stimulating factor-3 (cardiotrophin-like cytokine) on B cell function.
  • CD4 and CD8 T cells in susceptibility/protection to collagen-induced arthritis in HLA-DQ8-transgenic mice: implications for rheumatoid arthritis.
  • Activation of Ras and the mitogen-activated protein kinase pathway promotes protein degradation in muscle cells of Caenorhabditis elegans.
  • Amino acids in a region of ataxin-1 outside of the polyglutamine tract influence the course of disease in SCA1 transgenic mice.
  • Inhibition of breast tumor progression by systemic delivery of the maspin gene in a syngeneic tumor model.
  • Generation and characterization of malaria-specific human CD8(+) lymphocyte clones: effect of natural polymorphism on T cell recognition and endogenous cognate antigen presentationby liver cells.
  • In muro fragmentation of the rhamnogalacturonan I backbone in potato (Solanum tuberosum L.) results in a reduction and altered location of the galactan and arabinan side-chains and abnormal periderm development.
  • Transgenic interleukin 2 secreted by CML dendritic cells stimulates autologous T(H)1 T cells.
  • Accumulation of plant small heat-stress proteins in storage organs.
  • Transformed bacterial symbionts re-introduced to and detected in host gut.
  • Immunohistochemical comparison of alpha- and beta-synuclein in adult rat central nervous system.
  • Overexpression of Smad7 results in severe pathological alterations in multiple epithelial tissues.
  • RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation.
  • Manganese superoxide dismutase deficiency enhances cell turnover via tumor promoter-induced alterations in AP-1 and p53-mediated pathways in a skin cancer model.
  • Expression of biologically active human tumor necrosis factor-alpha in transgenic potato plant.
  • Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1.
  • Methamphetamine-induced neurotoxicity is attenuated in transgenic mice with a null mutation for interleukin-6.
  • Calreticulin is essential for cardiac development.
  • Constitutive telomerase expression promotes mammary carcinomas in aging mice.
  • Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines.
  • Taste receptor cell responses to the bitter stimulus denatonium involve Ca2+ influx via store-operated channels.
  • Effect of precursor feeding on alkaloid accumulation by a tryptophan decarboxylase over-expressing transgenic cell line T22 of Catharanthus roseus.
  • Alterations in behavior, amyloid beta-42, caspase-3, and Cox-2 in mutant PS2 transgenic mouse model of Alzheimer's disease.
  • Hematopoietic origin of glomerular mesangial cells.
  • Bcl-2 overexpression does not enhance in vivo axonal regeneration of retinal ganglion cells after peripheral nerve transplantation in adult mice.
  • Synthesis of a novel class of polyhydroxyalkanoates in Arabidopsis peroxisomes, and their use in monitoring short-chain-length intermediates of beta-oxidation.
  • Immunoglobulin heavy chain transgenic mice expressing Galalpha(1,3)Gal-reactive antibodies.
  • Transgenic mice overexpressing soluble osteoclast differentiation factor (sODF) exhibit severe osteoporosis.
  • Prionization of the Pichia methanolica SUP35 gene product in the yeast Saccharomyces cerevisiae
  • Characterization of an ultra-violet inducible gene that encodes glutathione S-transferase in Arabidopsis thaliana
  • Conservation of the function of DMRT1 regulatory sequences in mammalian sex differentiation.
  • Hypothalamic growth hormone secretagogue receptor regulates growth hormone secretion, feeding, and adiposity.
  • Downregulation of a chloroplast-targeted beta-amylase leads to a starch-excess phenotype in leaves.
  • Muscle expression of human retinol-binding protein (RBP). Suppression of the visual defect of RBP knockout mice.
  • Failure of HY-specific thymocytes to escape negative selection by receptor editing.
  • The G gamma / T-15 transgenic mouse model of androgen-independent prostate cancer: target cells of carcinogenesis and the effect of the vitamin D analogue EB 1089.
  • Prevalence of HTLV-I Tax in a subset of patients with rheumatoid arthritis.
  • Control of intercalation is cell-autonomous in the notochord of Ciona intestinalis.
  • Expression of recombinant trichosanthin, a ribosome-inactivating protein, in transgenic tobacco.
  • Insulin-like 3/relaxin-like factor gene mutations are associated with cryptorchidism.
  • A tumor-homing peptide with a targeting specificity related to lymphatic vessels.
  • Efficient generation of alpha(1,3) galactosyltransferase knockout porcine fetal fibroblasts for nuclear transfer.
  • Avidin expressed in transgenic tobacco leaves confers resistance to two noctuid pests, Helicoverpa armigera and Spodoptera litura.
  • Micro-dystrophin cDNA ameliorates dystrophic phenotypes when introduced into mdx mice as a transgene.
  • Enhanced SUMOylation in polyglutamine diseases.
  • Channel-mediated water movement across enclosed or perfused mouse intrahepatic bile duct units.
  • Epidermal growth factor receptor mediates increased cell proliferation, migration, and aggregation in esophageal keratinocytes in vitro and in vivo.
  • Transgenic overexpression of amphiregulin induces a mitogenic response selectively in pancreatic duct cells.
  • Attenuation of retinal photooxidative damage in thioredoxin transgenic mice.
  • A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice.
  • Tetracycline-inducible system for photoreceptor-specific gene expression.
  • Upregulation of neuronal nicotinic receptor subunits alpha4, beta2, and alpha7 in transgenic mice overexpressing human acetylcholinesterase.
  • Involvement of the Arabidopsis alpha-DOX1 fatty acid dioxygenase in protection against oxidative stress and cell death.
  • Pulmonary type II cell hypertrophy and pulmonary lipoproteinosis are features of chronic IL-13 exposure.
  • Adaptive evolution of small heat shock protein/alpha B-crystallin promoter activity of the blind subterranean mole rat, Spalax ehrenbergi.
  • Establishment and characterization of immortal hepatocytes derived from various transgenic mouse lines.
  • Disruption of dynein/dynactin inhibits axonal transport in motor neurons causing late-onset progressive degeneration.
  • Cardiac function and electrical remodeling of the calcineurin-overexpressed transgenic mouse.
  • Expression of a truncated Brca1 protein delays lactational mammary development in transgenic mice.
  • Transduction of dendritic cells by antigen-encoding lentiviral vectors permits antigen processing and MHC class I-dependent presentation.
  • Connexin 32 fused to the green fluorescent protein retains its ability to control the proliferation of thyroid cells.
  • Modeling a prion protein dimer: predictions for fibril formation.
  • A viral protein suppresses RNA silencing and binds silencing-generated, 21- to 25-nucleotide double-stranded RNAs.
  • The role of dopamine in motor symptoms in the R6/2 transgenic mouse model of Huntington's disease.
  • Maintenance of size and function of influenza virus hemagglutinin specific transgenic T-cell clone during life.
  • Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice.
  • Evidence for a Ustilago maydis steroid 5alpha-reductase by functional expression in Arabidopsis det2-1 mutants.
  • Transgenic expression of CD40 ligand produces an in vivo antitumor immune response against both CD40(+) and CD40(-) plasmacytoma cells.
  • A novel positive transcriptional feedback loop in midbrain-hindbrain boundary development is revealed through analysis of the zebrafish pax2.1 promoter in transgenic lines.
  • APRIL modulates B and T cell immunity.
  • Biological activity of human granulocyte-macrophage colony stimulating factor is maintained in a fusion with seed glutelin peptide.
  • Functional expression of a bovine major histocompatibility complex class I gene in transgenic mice.
  • The formation of highly soluble oligomers of alpha-synuclein is regulated by fatty acids and enhanced in Parkinson's disease.
  • Reduced hypertension-induced end-organ damage in mice lacking cardiac and renal angiotensinogen synthesis.
  • Modulation of microvascular signaling by heparan sulfate matrix: studies in syndecan-4 transgenic mice.
  • Effects of transgenic bt corn on growth and development of the stalk borer Papaipema nebris (Lepidoptera: Noctuidae).
  • A cathepsin L protease essential for Caenorhabditis elegans embryogenesis is functionally conserved in parasitic nematodes.
  • Contribution of IL-18 to Th1 response and host defense against infection by Mycobacterium tuberculosis: a comparative study with IL-12p40.
  • Efficient isolation of novel human monoclonal antibodies with neutralizing activity against HIV-1 from transgenic mice expressing human Ig loci.
  • Engraftment of bone marrow and fetal liver cells after in utero transplantation in MDX mice.
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  • Ethylene insensitivity impairs resistance to soilborne pathogens in tobacco and Arabidopsis thaliana.
  • Ntlim1, a PAL-box binding factor, controls promoter activity of the horseradish wound-inducible peroxidase gene.
  • A DNase I hypersensitive site near the murine gamma1 switch region contributes to insertion site independence of transgenes and modulates the amount of transcripts induced by CD40 ligation.
  • Gibberellin regulates post-microsporogenesis processes in petunia anthers.
  • Myeloid, B and T lymphoid and mixed lineage thymic lymphomas in the irradiated mouse.
  • BCR/ABL P190 transgenic mice develop leukemia in the absence of Crkl.
  • Functional effects of eotaxin are selectively upregulated on IL-5 transgenic mouse eosinophils.
  • Structural basis for the modulation of lignin monomer methylation by caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase.
  • The plastidic 2-cysteine peroxiredoxin is a target for a thioredoxin involved in the protection of the photosynthetic apparatus against oxidative damage.
  • Production of a cytochrome P450 2E1 transgenic mouse and initial evaluation of alcoholic liver damage.
  • A change in the conformation of prions accompanies the emergence of a new prion strain.
  • Induction of ovarian cancer by defined multiple genetic changes in a mouse model system.
  • Analysis of the individual role of the TCRzeta chain in transgenic mice after conditional activation with chemical inducers of dimerization.
  • Early loss of synaptic protein PSD-95 from rod terminals of rhodopsin P347L transgenic porcine retina.
  • Stimulation of 3T3-L1 adipogenesis by signal transducer and activator of transcription 5.
  • A long-term culture system for olfactory explants with intrinsically fluorescent cell populations.
  • Integrins regulate DLG/FAS2 via a CaM kinase II-dependent pathway to mediate synapse elaboration and stabilization during postembryonic development.
  • Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain.
  • USP7, a ubiquitin-specific protease, interacts with ataxin-1, the SCA1 gene product.
  • Contributions of the T cell receptor-associated CD3gamma-ITAM to thymocyte selection.
  • Promoter-proximal tethering elements regulate enhancer-promoter specificity in the Drosophila Antennapedia complex.
  • EDA targets revealed by skin gene expression profiles of wild-type, Tabby and Tabby EDA-A1 transgenic mice.
  • Obtaining stem borer-resistant homozygous transgenic lines of Minghui 81 harboring novel cry1Ac gene via particle bombardment
  • The role of MSX1 in human tooth agenesis.
  • Tamoxifen mutagenesis and carcinogenesis in livers of lambda/lacI transgenic rats: selective influence of phenobarbital promotion.
  • Thymic and extrathymic T cell development pathways follow different rules.
  • Transgenic calmodulin-dependent protein kinase II activation: dose-dependent effects on synaptic plasticity, learning, and memory.
  • Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies.
  • A point mutant of GAP-43 induces enhanced short-term and long-term hippocampal plasticity.
  • Progressive appearance of pigmentation in amelanotic melanoma lesions.
  • Deficient expression of insulin receptor substrate-1 (IRS-1) fails to block insulin-like growth factor-I (IGF-I) stimulation of brain growth and myelination.
  • Adenovirus-mediated gene transfer of glial cell line-derived neurotrophic factor prevents motor neuron loss of transgenic model mice for amyotrophic lateral sclerosis.
  • Alterations in cytokine regulation in aged epidermis: implications for permeability barrier homeostasis and inflammation. I. IL-1 gene family.
  • Expression of human apolipoprotein E downregulates amyloid precursor protein-induced ischemic susceptibility.
  • Molecular profiling of angiogenesis markers.
  • Sperm-mediated transformation of the honey bee, Apis mellifera.
  • Estrogenic activity of UV filters determined by an in vitro reporter gene assay and an in vivo transgenic zebrafish assay.
  • Hepatocyte nuclear factor 3beta inhibits hepatitis B virus replication in vivo.
  • Comparison of kinetics of induction of DNA adducts and gene mutations by a nitrofuran compound, 7-methoxy-2-nitronaphtho2,1-bfuran (R7000), in the caecum and small intestine of Big Blue mice.
  • Oligogalacturonides inhibit the induction of late but not of early auxin-responsive genes in tobacco.
  • Regeneration of transgenic citrus plants under non selective conditions results in high-frequency recovery of plants with silenced transgenes.
  • Differential neuropathological alterations in transgenic mice expressing alpha-synuclein from the platelet-derived growth factor and Thy-1 promoters.
  • Heterologous expression of a bacterial homospermidine synthase gene in transgenic tobacco: effects on the polyamine pathway.
  • Effects of Fragile X syndrome and an FMR1 knockout mouse model on forebrain neuronal cell biology.
  • Characterization of human membrane cofactor protein (MCP; CD46) on spermatozoa.
  • Expression of Cre Recombinase in the developing mouse limb bud driven by a Prxl enhancer.
  • Cardiac expression of a gain-of-function alpha(5)-integrin results in perinatal lethality.
  • Control of syngeneic tumor growth by activation of CD8+ T cells: efficacy is limited by migration away from the site and induction of nonresponsiveness.
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  • Selection of transgenic Xenopus laevis using antibiotic resistance.
  • Osteopontin plays an important role in the development of medial thickening and neointimal formation.
  • Effect of yeast CTA1 gene expression on response of tobacco plants to tobacco mosaic virus infection.
  • Distinct physiological roles of fructokinase isozymes revealed by gene-specific suppression of Frk1 and Frk2 expression in tomato.
  • The role of ethylene and wound signaling in resistance of tomato to Botrytis cinerea.
  • Thrombospondin-1 selectively inhibits early-stage carcinogenesis and angiogenesis but not tumor lymphangiogenesis and lymphatic metastasis in transgenic mice.
  • Significant impact of the highly informative (CA)n repeat polymorphism of the APOA-II gene on the plasma APOA-II concentrations and HDL subfractions: The ECTIM study.
  • Translational repression by MSY4 inhibits spermatid differentiation in mice.
  • Cblb is a major susceptibility gene for rat type 1 diabetes mellitus.
  • Cell division is not a "clock" measuring acquisition of competence to produce IFN-gamma or IL-4.
  • Early onset of chondroitin sulfate and osteopontin expression in angiotensin II-dependent left ventricular hypertrophy.
  • Human sterol 27-hydroxylase (CYP27) overexpressor transgenic mouse model. Evidence against 27-hydroxycholesterol as a critical regulator of cholesterol homeostasis.
  • A surveillance system regulates selective entry of RNA into the shoot apex.
  • Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice.
  • Conifer reproductive development involves B-type MADS-box genes with distinct and different activities in male organ primordia.
  • Direct autoregulation and gene dosage compensation by POU-domain transcription factor Brn3a.
  • D1 dopamine receptor regulation of microtubule-associated protein-2 phosphorylation in developing cerebral cortical neurons.
  • Murine peripherin gene sequences direct Cre recombinase expression to peripheral neurons in transgenic mice.
  • Cardioselective overexpression of HO-1 prevents I/R-induced cardiac dysfunction and apoptosis.
  • An ex vivo murine model to study poliovirus-induced apoptosis in nerve cells.
  • Control of T cell development in vivo by subdomains within the IL-7 receptor alpha-chain cytoplasmic tail.
  • Transgenic expression of the protein-L-isoaspartyl methyltransferase (PIMT) gene in the brain rescues mice from the fatal epilepsy of PIMT deficiency.
  • Expression of TGF-beta type II receptors in the olfactory epithelium and their regulation in TGF-alpha transgenic mice.
  • Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site.
  • Expression of a vas::EGFP transgene in primordial germ cells of the zebrafish.
  • Mutant products of the NF2 tumor suppressor gene are degraded by the ubiquitin-proteasome pathway.
  • Hepatitis C virus core inhibits the Fas-mediated p38 mitogen activated kinase signaling pathway in hepatocytes.
  • Down-regulation of DR12, an auxin-response-factor homolog, in the tomato results in a pleiotropic phenotype including dark green and blotchy ripening fruit.
  • Leukocyte infiltration, but not neurodegeneration, in the CNS of transgenic mice with astrocyte production of the CXC chemokine ligand 10.
  • Cloned zebrafish by nuclear transfer from long-term-cultured cells.
  • Bovine blastocyst development from oocytes injected with freeze-dried spermatozoa.
  • Functional characterization of the EMCV IRES in plants.
  • Estrogen receptor alpha, but not estrogen receptor beta, is involved in the regulation of the hair follicle cycling as well as the thickness of epidermis in male mice.
  • Yellow lupine gene encoding stearoyl-ACP desaturase--organization, expression and potential application.
  • Human CLC-KB gene promoter drives the EGFP expression in the specific distal nephron segments and inner ear.
  • A set of modular plant transformation vectors allowing flexible insertion of up to six expression units.
  • Expression of protective antigen in transgenic plants: a step towards edible vaccine against anthrax.
  • Significance of xanthine oxidase in the production of intracellular oxygen radicals in an in-vitro hypoxia-reoxygenation model.
  • Characterization of a mouse tet-on glia precursor cell line in vitro and in vivo using the electrophysiological measurement.
  • Transformation of Neomycin Resistance Gene (neo(R)) into Silkworm (Bombyx mori.L.).
  • Transgenic mice expressing human copper-zinc superoxide dismutase exhibit attenuated apparent diffusion coefficient reduction during reperfusion following focal cerebral ischemia.
  • Deficiency of survivin in transgenic mice exacerbates Fas-induced apoptosis via mitochondrial pathways.
  • Gene transfer into the fetal primate: evidence for the secretion of transgene product.
  • Effect on motor neuron survival in mutant SOD1 (G93A) transgenic mice by Bcl-2 expression using retrograde axonal transport of adenoviral vectors.
  • B and T cell tolerance and autoimmunity in autoantibody transgenic mice.
  • Overexpression of RCN1 and RCN2, rice TERMINAL FLOWER 1/CENTRORADIALIS homologs, confers delay of phase transition and altered panicle morphology in rice.
  • Transgenic rats carrying human c-Ha-ras proto-oncogene are highly susceptible to N-nitrosomethylbenzylamine induction of esophageal tumorigenesis.
  • Functional alteration of the somatotrophic axis in transgenic mice with liver-specific expression of human insulin-like growth factor binding protein-1.
  • Androgen-dependent mammary carcinogenesis in rats transgenic for the Neu proto-oncogene.
  • Characterization of the murine Timp4 gene, localization within intron 5 of the synapsin 2 gene and tissue distribution of the mRNA.
  • Recruitment of the kainate receptor subunit glutamate receptor 6 by cadherin/catenin complexes.
  • Autophagy in hypothalamic neurones of rats expressing a familial neurohypophysial diabetes insipidus transgene.
  • Augmented expression of tumour necrosis factor-alpha induced by lipopolysaccharide in spleen of human monocyte chemoattractant protein-1 transgenic mouse enhances the lipopolysaccharide sensitivity of the marginal zone macrophages.
  • RNAs 1 and 2 of Alfalfa mosaic virus, expressed in transgenic plants, start to replicate only after infection of the plants with RNA 3.
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  • Effect of monoamine oxidase A knockout on resistance to long-term exposure to ethanol.
  • Beta-amyloid-associated expression of intercellular adhesion molecule-1 in brain cortical tissue of transgenic Tg2576 mice.
  • Two low-temperature-inducible Chlorella genes for delta12 and omega-3 fatty acid desaturase (FAD): isolation of delta12 and omega-3 fad cDNA clones, expression of delta12 fad in Saccharomyces cerevisiae, and expression of omega-3 fad in Nicotiana tabacum.
  • Expression of renin in large arteries outside the kidney revealed by human renin promoter/LacZ transgenic mouse.
  • In vivo bradykinin B2 receptor activation reduces renal fibrosis.
  • Reversibility of pulmonary abnormalities by conditional replacement of surfactant protein D (SP-D) in vivo.
  • Labeling of cerebral amyloid beta deposits in vivo using intranasal basic fibroblast growth factor and serum amyloid P component in mice.
  • Expression of desmoglein 1 compensates for genetic loss of desmoglein 3 in keratinocyte adhesion.
  • Editing autoreactive TCR enables efficient positive selection.
  • Greenhouse and field testing of transgenic wheat plants stably expressing genes for thaumatin-like protein, chitinase and glucanase against Fusarium graminearum.
  • Specimen block counter-staining for localization of GUS expression in transgenic arabidopsis and tobacco.
  • A regression-based method to identify differentially expressed genes in microarray time course studies and its application in an inducible Huntington's disease transgenic model.
  • Activation of different Wnt/beta-catenin signaling components in mammary epithelium induces transdifferentiation and the formation of pilar tumors.
  • Transcript abundance in mouse pituitaries with altered growth hormone expression quantified by reverse transcriptase polymerase chain reaction implicates transcription factor Zn-16 in gene regulation in vivo.
  • Bee venom phospholipase inhibits malaria parasite development in transgenic mosquitoes.
  • Inducible expression of FGF-3 in mouse mammary gland.
  • Cholesteryl ester transfer protein expressed in lecithin cholesterol acyltransferase-deficient mice.
  • Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4).
  • A promoter from the loblolly pine PtNIP1;1 gene directs expression in an early-embryogenesis and suspensor-specific fashion.
  • Long-term exposure of E-mu-Pim1 transgenic mice to 898.4 MHz microwaves does not increase lymphoma incidence.
  • The Arabidopsis PHD-finger protein SHL is required for proper development and fertility.
  • Body composition, bone mass and microstructural analysis in GH-transgenic mice reveals that skeletal changes are specific to bone compartment and gender.
  • Morphogenetic changes in ambiol-treated regenerates of parent and transgenic potato plants
  • Combined expression of S-VSPalpha in two different organelles enhances its accumulation and total lysine production in leaves of transgenic tobacco plants.
  • In vivo labeling of parvalbumin-positive interneurons and analysis of electrical coupling in identified neurons.
  • Deficits in trace cued fear conditioning in galanin-treated rats and galanin-overexpressing transgenic mice.
  • The generation and characterization of potentially therapeutic Abeta antibodies in mice: differences according to strain and immunization protocol.
  • Down-regulation of tomato beta-galactosidase 4 results in decreased fruit softening.
  • Reproductive performance of a transgenic boar carrying the bovine growth hormone gene (bGH).
  • Transgenic strategy for demonstrating nuclear reprogramming in the mouse.
  • Regulation of parietal cell migration by gastrin in the mouse.
  • Conservation and elaboration of Hox gene regulation during evolution of the vertebrate head.
  • High molecular weight RNAs and small interfering RNAs induce systemic posttranscriptional gene silencing in plants.
  • Sequence-, tissue-, and delivery-specific targeting of RNA during post-transcriptional gene silencing.
  • Tomato LeAGP-1 arabinogalactan-protein purified from transgenic tobacco corroborates the Hyp contiguity hypothesis.
  • Neonatal neuronal overexpression of glycogen synthase kinase-3 beta reduces brain size in transgenic mice.
  • Definition of additional functional ligands for Ly49I(B6) using FVBLy49I(B6) transgenic mice and B6 natural killer cell effectors.
  • Silencing of a viral RNA silencing suppressor in transgenic plants.
  • Notch1 control of oligodendrocyte differentiation in the spinal cord.
  • In silico and in situ characterization of the zebrafish (Danio rerio) gnrh3 (sGnRH) gene.
  • Hematoprotection and enrichment of transduced cells in vivo after gene transfer of MGMT(P140K) into hematopoietic stem cells.
  • Chondromodulin I is dispensable during enchondral ossification and eye development.
  • Distribution and ultrastructure of interstitial cells of Cajal in the mouse colon, using antibodies to Kit and Kit(W-lacZ) mice.
  • Tissue-dependent expression of matrix proteins in human endothelin-1 transgenic mice.
  • Ovarian hyperstimulation by LH leads to mammary gland hyperplasia and cancer predisposition in transgenic mice.
  • Chromosome assignment of Cd36 transgenes in two rat SHR lines by FISH and linkage mapping of transgenic insert in the SHR-TG19 line.
  • Lethal shock induced by streptococcal pyrogenic exotoxin A in mice transgenic for human leukocyte antigen-DQ8 and human CD4 receptors: implications for development of vaccines and therapeutics.
  • Erythroid expression of the human alpha-spectrin gene promoter is mediated by GATA-1- and NF-E2-binding proteins.
  • Unhampered prion neuroinvasion despite impaired fast axonal transport in transgenic mice overexpressing four-repeat tau.
  • Constitutive activation and transgenic evaluation of the function of an arabidopsis PKS protein kinase.
  • G protein subunit G gamma 13 is coexpressed with G alpha o, G beta 3, and G beta 4 in retinal ON bipolar cells.
  • F-MuLV acceleration of myelomonocytic tumorigenesis in SV40 large T antigen transgenic mice is accompanied by retroviral insertion at Fli1 and a novel locus, Fim4.
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  • Cardiac-specific abrogation of NF- kappa B activation in mice by transdominant expression of a mutant I kappa B alpha.
  • Discrete domains mediate the light-responsive nuclear and cytoplasmic localization of Arabidopsis COP1.
  • Position-independent and tissue-specific expression of porcine whey acidic protein gene from a bacterial artificial chromosome in transgenic mice.
  • Temporal Cre-mediated recombination exclusively in endothelial cells using Tie2 regulatory elements.
  • Expression profiles of the essential intermediate filament (IF) protein A2 and the IF protein C2 in the nematode Caenorhabditis elegans.
  • Mice deficient in TNF receptors are protected against dopaminergic neurotoxicity: implications for Parkinson's disease.
  • Immunohistochemical and electron microscopic study of invasion and differentiation in spinal cord lesion of neural stem cells grafted through cerebrospinal fluid in rat.
  • Development and characterization of conditionally immortalized gastric epithelial cell lines from transgenic rats harboring temperature-sensitive simian virus 40 large T-antigen gene.
  • Neural CAMS and their role in the development and organization of myelin sheaths.
  • Copper deficiency induced by tetrathiomolybdate suppresses tumor growth and angiogenesis.
  • Overexpression of ABCG5 and ABCG8 promotes biliary cholesterol secretion and reduces fractional absorption of dietary cholesterol.
  • Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER-2/neu transgenic mice.
  • Androgen-dependent regulation of human angiotensinogen expression in KAP-hAGT transgenic mice.
  • Progressive prostate hyperplasia in adult prolactin transgenic mice is not dependent on elevated serum androgen levels.
  • Alterations in matrix metalloproteinase-9 levels and tissue inhibitor of matrix metalloproteinases-1 expression in a transforming growth factor-beta transgenic model of hydrocephalus.
  • Calpain inhibitors: a treatment for Alzheimer's disease.
  • Development of a new treatment for Alzheimer's disease and Parkinson's disease using anti-aggregatory beta-synuclein-derived peptides.
  • Overexpression of the wheat FK506-binding protein 73 (FKBP73) and the heat-induced wheat FKBP77 in transgenic wheat reveals different functions of the two isoforms.
  • The use of the uromodulin promoter to target production of recombinant proteins into urine of transgenic animals.
  • Instrumental activation of bid by caspase-1 in a transgenic mouse model of ALS.
  • Pathway pathology: histological differences between ErbB/Ras and Wnt pathway transgenic mammary tumors.
  • Electrical and chemical synapses among parvalbumin fast-spiking GABAergic interneurons in adult mouse neocortex.
  • Transgenic barley grain overexpressing thioredoxin shows evidence that the starchy endosperm communicates with the embryo and the aleurone.
  • Cytochrome p450 CYP79F1 from arabidopsis catalyzes the conversion of dihomomethionine and trihomomethionine to the corresponding aldoximes in the biosynthesis of aliphatic glucosinolates.
  • Binding of p190RhoGEF to a destabilizing element on the light neurofilament mRNA is competed by BC1 RNA.
  • Suppression of transgene silencing by matrix attachment regions in maize: a dual role for the maize 5' ADH1 matrix attachment region.
  • Isotype switch-mediated CH deletions are a recurrent feature of Myc/CH translocations in peritoneal plasmacytomas in mice.
  • In vivo evidence that BMP signaling is necessary for apoptosis in the mouse limb.
  • Anti-human CD4 induces peripheral tolerance in a human CD4+, murine CD4-, HLA-DR+ advanced transgenic mouse model.
  • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade.
  • Natural killer cells contribute to the lethality of a murine model of Escherichia coli infection.
  • Overexpression of TIAP/m-survivin in thymocytes enhances cell proliferation.
  • Differential vulnerability of cranial motoneurons in mouse models with motor neuron degeneration.
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  • Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice.
  • Analysis of cis-sequence of subgenomic transcript promoter from the Figwort mosaic virus and comparison of promoter activity with the cauliflower mosaic virus promoters in monocot and dicot cells.
  • Insulin-like growth factor binding protein-5 (IGFBP-5) induces premature cell death in the mammary glands of transgenic mice.
  • Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.
  • Reduction of Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase by Antisense RNA in the C4 Plant Flaveria bidentis Leads to Reduced Assimilation Rates and Increased Carbon Isotope Discrimination.
  • 8prime-Methylene Abscisic Acid (An Effective and Persistent Analog of Abscisic Acid).
  • Structural Characterization of Modified Lignin in Transgenic Tobacco Plants in Which the Activity of 4-Coumarate:Coenzyme A Ligase Is Depressed.
  • Reduced Lignin Content and Altered Lignin Composition in Transgenic Tobacco Down-Regulated in Expression of L-Phenylalanine Ammonia-Lyase or Cinnamate 4-Hydroxylase.
  • Antisense Repression of Both ADP-Glucose Pyrophosphorylase and Triose Phosphate Translocator Modifies Carbohydrate Partitioning in Potato Leaves.
  • The Effects of Salicylic Acid and Tobacco Mosaic Virus Infection on the Alternative Oxidase of Tobacco.
  • Increased Salt and Drought Tolerance by D-Ononitol Production in Transgenic Nicotiana tabacum L.
  • Blocking histone deacetylation in Arabidopsis induces pleiotropic effects on plant gene regulation and development.
  • JunB and Bcl-2 overexpression results in protection against cell death of nigral neurons following axotomy.
  • Requirements for intron-mediated enhancement of gene expression in Arabidopsis.
  • The Competence of Maize Shoot Meristems for Integrative Transformation and Inherited Expression of Transgenes.
  • Analysis of Cytokinin Metabolism in ipt Transgenic Tobacco by Liquid Chromatography-Tandem Mass Spectrometry.
  • Lhcb Transcription Is Coordinated with Cell Size and Chlorophyll Accumulation (Studies on Fluorescence-Activated, Cell-Sorter-Purified Single Cells from Wild-Type and immutans Arabidopsis thaliana).
  • Overexpression of L-Phenylalanine Ammonia-Lyase in Transgenic Tobacco Plants Reveals Control Points for Flux into Phenylpropanoid Biosynthesis.
  • Arabidopsis CYP98A3 mediating aromatic 3-hydroxylation. Developmental regulation of the gene, and expression in yeast.
  • Activation of pyk2/related focal adhesion tyrosine kinase and focal adhesion kinase in cardiac remodeling.
  • Developmental and Hormonal Regulation of Rice alpha-Amylase(RAmy1A)-gusA Fusion Genes in Transgenic Rice Seeds.
  • Decrease in Activity of Glutathione Reductase Enhances Paraquat Sensitivity in Transgenic Nicotiana tabacum.
  • Apolipoprotein A-II: beyond genetic associations with lipid disorders and insulin resistance.
  • The 5prime Flanking Regions of Vicilin and Napin Storage Protein Genes Are Down-Regulated by Desiccation in Transgenic Tobacco.
  • Violaxanthin Cycle Pigment Contents in Potato and Tobacco Plants with Genetically Reduced Photosynthetic Capacity.
  • Partial rescue of insulin receptor-deficient mice by transgenic complementation with an activated insulin receptor in the liver.
  • Altered Growth and Wood Characteristics in Transgenic Hybrid Aspen Expressing Agrobacterium tumefaciens T-DNA Indoleacetic Acid-Biosynthetic Genes.
  • Overexpression of c-myc in diabetic mice restores altered expression of the transcription factor genes that regulate liver metabolism.
  • Feasibility of using autologous transplantation to evaluate hematopoietic stem cell-based gene therapy strategies in transgenic mouse models of human disease.
  • Bleomycin sensitivity of mice expressing dominant-negative p53 in the lung epithelium.
  • Age-dependent synapse withdrawal at axotomised neuromuscular junctions in Wld(s) mutant and Ube4b/Nmnat transgenic mice.
  • Only Specific Tobacco (Nicotiana tabacum) Chitinases and beta-1,3-Glucanases Exhibit Antifungal Activity.
  • Ripening Physiology of Fruit from Transgenic Tomato (Lycopersicon esculentum) Plants with Reduced Ethylene Synthesis.
  • Identification of genes encoding receptor-like protein kinases as possible targets of pathogen- and salicylic acid-induced WRKY DNA-binding proteins in Arabidopsis.
  • Use of Transgenic Plants with Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase Antisense DNA to Evaluate the Rate Limitation of Photosynthesis under Water Stress.
  • Generation of Large Numbers of Independently Transformed Fertile Barley Plants.
  • Agrobacterium-Mediated Transformation of Subterranean Clover (Trifolium subterraneum L.).
  • Complementation of the Tomato anthocyanin without (aw) Mutant Using the Dihydroflavonol 4-Reductase Gene.
  • Rice Triosephosphate Isomerase Gene 5prime Sequence Directs beta-Glucuronidase Activity in Transgenic Tobacco but Requires an Intron for Expression in Rice.
  • Alteration of the Amount of the Chloroplast Phosphate Translocator in Transgenic Tobacco Affects the Distribution of Assimilate between Starch and Sugar.
  • Establishment of animal model of antigen-specific T lymphocyte recruitment into nasal mucosa.
  • Evidence for dysfunction of the nigrostriatal pathway in the R6/1 line of transgenic Huntington's disease mice.
  • Dissecting the oncogenic potential of Gli2: deletion of an NH(2)-terminal fragment alters skin tumor phenotype.
  • The Kruppel-like factor Zf9 and proteins in the Sp1 family regulate the expression of HSP47, a collagen-specific molecular chaperone.
  • Loss of p27(Kip1) cooperates with cyclin E in T-cell lymphomagenesis.
  • Fast synaptic inhibition promotes synchronized gamma oscillations in hippocampal interneuron networks.
  • A Mutant S3 RNase of Petunia inflata Lacking RNase Activity Has an Allele-Specific Dominant Negative Effect on Self-Incompatibility Interactions.
  • Akt induces enhanced myocardial contractility and cell size in vivo in transgenic mice.
  • Transgenic mice overexpressing insulin-like growth factor binding protein-5 display transiently decreased osteoblastic function and osteopenia.
  • Transgenic mice harboring murine luteinizing hormone receptor promoter/beta-galactosidase fusion genes: different structural and hormonal requirements of expression in the testis, ovary, and adrenal gland.
  • RNA-Mediated Virus Resistance: Role of Repeated Transgenes and Delineation of Targeted Regions.
  • Two Small Spatially Distinct Regions of Phytochrome B Are Required for Efficient Signaling Rates.
  • Immortalized renal proximal and collecting duct cell lines derived from transgenic mice harboring L-type pyruvate kinase promoters as tools for pharmacological and toxicological studies.
  • Drosophila acid DNase is a homolog of mammalian DNase II.
  • Cooperation between p53 mutation and high telomerase transgenic expression in spontaneous cancer development.
  • The spinocerebellar ataxia type 1 protein, ataxin-1, has RNA-binding activity that is inversely affected by the length of its polyglutamine tract.
  • Coordinated Activation of Programmed Cell Death and Defense Mechanisms in Transgenic Tobacco Plants Expressing a Bacterial Proton Pump.
  • Suppression and Restoration of Lesion Formation in Arabidopsis lsd Mutants.
  • Aberrant expression of the Arabidopsis circadian-regulated APRR5 gene belonging to the APRR1/TOC1 quintet results in early flowering and hypersensitiveness to light in early photomorphogenesis.
  • Functional analysis of cis-regulatory elements controlling initiation and maintenance of early Cdx1 gene expression in the mouse.
  • Optimal colocalization of TCR and CD8 as a novel mechanism for the control of functional avidity.
  • B6 strain Ly49I inhibitory gene expression on T cells in FVB.Ly49IB6 transgenic mice fails to prevent normal T cell functions.
  • Genetic diversity and selection in the maize starch pathway.
  • Reduced Position Effect in Mature Transgenic Plants Conferred by the Chicken Lysozyme Matrix-Associated Region.
  • Carbon assimilation and metabolism in potato leaves deficient in plastidial phosphoglucomutase.
  • The modulation of cellular susceptibility to oxidative stress: protective and destructive actions of Cu,Zn-superoxide dismutase.
  • DNA methylation and chromatin structure affect transcriptional and post-transcriptional transgene silencing in Arabidopsis.
  • Genetic Ablation of Floral Cells in Arabidopsis.
  • Heritable endogenous gene regulation in plants with designed polydactyl zinc finger transcription factors.
  • In vivo effects of CETP inhibitory peptides in hypercholesterolemic rabbit and cholesteryl ester transfer protein-transgenic mice.
  • Neuronal leucine-rich repeat protein-3 amplifies MAPK activation by epidermal growth factor through a carboxyl-terminal region containing endocytosis motifs.
  • Intracytoplasmic sperm injection is more efficient than in vitro fertilization for generating mouse embryos from cryopreserved spermatozoa.
  • An Antisense Pectin Methylesterase Gene Alters Pectin Chemistry and Soluble Solids in Tomato Fruit.
  • Dietary catechin delays tumor onset in a transgenic mouse model.
  • Characterization of an inducible promoter system in Catharanthus roseus hairy roots.
  • Abscisic Acid Mediates Wound Induction but Not Developmental-Specific Expression of the Proteinase Inhibitor II Gene Family.
  • Cell-to-cell movement of the PVX 12K, 8K, or coat proteins may depend on the host, leaf developmental stage, and the PVX 25K protein.
  • Cardiovascular effects of endothelin-1 and endothelin antagonists in conscious, hypertensive ((mRen-2)27) rats.
  • Overexpression of human hepatic lipase and ApoE in transgenic rabbits attenuates response to dietary cholesterol and alters lipoprotein subclass distributions.
  • Cyclin-dependent kinase-2 controls oligodendrocyte progenitor cell cycle progression and is downregulated in adult oligodendrocyte progenitors.
  • Facial nerve lesion response; strain differences but no involvement of IFN-gamma, STAT4 or STAT6.
  • Oxidative metabolism and the physiological age of seed potatoes are affected by increased alpha-linolenate content.
  • Transgenically encoded protein photoinactivation (FlAsH-FALI): acute inactivation of synaptotagmin I.
  • Dynamic organization of vacuolar and microtubule structures during cell cycle progression in synchronized tobacco BY-2 cells.
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  • Transient Gene Expression in Intact and Organized Rice Tissues.
  • Low docosahexaenoic acid levels in rod outer segments of rats with P23H and S334ter rhodopsin mutations.
  • Differential requirement of caspases during naive T cell proliferation.
  • Smooth muscle cells in transplant atherosclerotic lesions are originated from recipients, but not bone marrow progenitor cells.
  • The application of the restriction site mutation assay to compare 1-ethyl-1-nitrosourea-induced mutations between the endogenous p53 gene and the transgenic LacZ gene in MutaMouse testes.
  • Selective loss of neurofilament expression in Cu/Zn superoxide dismutase (SOD1) linked amyotrophic lateral sclerosis.
  • The ABCA1 transporter functions on the basolateral surface of hepatocytes.
  • Overexpression of hAPPswe impairs rewarded alternation and contextual fear conditioning in a transgenic mouse model of Alzheimer's disease.
  • Transgenic study of the function of chymase in heart remodeling.
  • Developmental toxicology of cadmium in living embryos of a stable transgenic zebrafish line.
  • Hypertension-linked decrease in the expression of brain gamma-adducin.
  • Fiber-type specific and position-dependent expression of a transgene in limb muscles.
  • Expression of transgene encoded TGF-beta in islets prevents autoimmune diabetes in NOD mice by a local mechanism.
  • Retinoic acid enhances the T helper 2 cell development that is essential for robust antibody responses through its action on antigen-presenting cells.
  • Tissue specificity of the Kaposi's sarcoma-associated herpesvirus latent nuclear antigen (LANA/orf73) promoter in transgenic mice.
  • Induction of Ltp (lipid transfer protein) and Pal (phenylalanine ammonia-lyase) gene expression in rice roots colonized by the arbuscular mycorrhizal fungus Glomus mosseae.
  • Multiple ubiquitin ligase-mediated processes require COP9 signalosome and AXR1 function.
  • Suppression of a ripening-related endo-1,4-beta-glucanase in transgenic pepper fruit does not prevent depolymerization of cell wall polysaccharides during ripening.
  • Expression patterns of two tobacco isoflavone reductase-like genes and their possible roles in secondary metabolism in tobacco.
  • The vascular expression pattern directed by the Eucalyptus gunnii cinnamyl alcohol dehydrogenase EgCAD2 promoter is conserved among woody and herbaceous plant species.
  • Gab1 and SHP-2 promote Ras/MAPK regulation of epidermal growth and differentiation.
  • A minimal IFN-gamma promoter confers Th1 selective expression.
  • A transgenic mouse model of autoimmune glomerulonephritis and necrotizing arteritis associated with cryoglobulinemia.
  • Elevated mutant frequencies and predominance of G:C to A:T transition mutations in Msh6(-/-) small intestinal epithelium.
  • Modeling Alzheimer's disease and other proteopathies in vivo: Is seeding the key? Review Article.
  • Lethal T cell immunodeficiency induced by chronic costimulation via CD27-CD70 interactions.
  • beta-site APP cleaving enzyme mRNA expression in APP transgenic mice: anatomical overlap with transgene expression and static levels with aging.
  • Establishment of transgenic Xenopus laevis by intracytoplasmic sperm injection
  • Mutations induced by alpha-hydroxytamoxifen in the lacI and cII genes of Big Blue transgenic rats.
  • The KNAT2 homeodomain protein interacts with ethylene and cytokinin signaling.
  • Change in superoxide dismutase 1 protein localization towards mitochondria: an immunohistochemical study in transgenic G93A mice.
  • The participation of P- and E-selectins on biomaterial-mediated tissue responses.
  • Partial rescue of taste responses of alpha-gustducin null mice by transgenic expression of alpha-transducin.
  • Titins in C.elegans with unusual features: coiled-coil domains, novel regulation of kinase activity and two new possible elastic regions.
  • Agrobacterium-mediated transformation of cauliflower: optimization of protocol and development of Bt-transgenic cauliflower.
  • Phototropin LOV domains exhibit distinct roles in regulating photoreceptor function.
  • Degeneration of corticospinal and bulbospinal systems in the superoxide dismutase 1(G93A G1H) transgenic mouse model of familial amyotrophic lateral sclerosis.
  • Bcl-2 inhibits apoptosis of spermatogonia and growth of spermatogonial stem cells in a cell-intrinsic manner.
  • Prevention of pathology in mdx mice by expression of utrophin: analysis using an inducible transgenic expression system.
  • A functional recombinant single-chain T cell receptor fragment capable of selectively targeting antigen-presenting cells.
  • Role of matrix metalloproteinases in kidney development and glomerulopathy: lessons from transgenic mice.
  • MHC class I and class II presentation of tumor antigen in retrovirally and adenovirally transduced dendritic cells.
  • Progastrin1-80 stimulates growth of intestinal epithelial cells in vitro via high-affinity binding sites.
  • Electrophysiological consequences of human IKs channel expression in adult murine heart.
  • Disease progression in a transgenic model of familial amyotrophic lateral sclerosis is dependent on both neuronal and non-neuronal zinc binding proteins.
  • Altered DNA mutation spectrum in aflatoxin b1-treated transgenic mice that express the hepatitis B virus x protein.
  • Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis.
  • Antagonistic variant virus prevents wild-type virus-induced lethal immunopathology.
  • Transgenic mice overexpressing leptin accumulate adipose mass at an older, but not younger, age.
  • T cell hyporesponsiveness induced by oral administration of ovalbumin is associated with impaired NFAT nuclear translocation and p27kip1 degradation.
  • Comparative effect of fenofibrate on hepatic desaturases in wild-type and peroxisome proliferator-activated receptor alpha-deficient mice.
  • Selective delivery of augmented IL-2 receptor signals to responding CD8+ T cells increases the size of the acute antiviral response and of the resulting memory T cell pool.
  • Transneuronal tracing of diverse CNS circuits by Cre-mediated induction of wheat germ agglutinin in transgenic mice.
  • Xanthones and secoiridoids from hairy root cultures of Centaurium erythraea and C. pulchellum.
  • Permeability transition-independent release of mitochondrial cytochrome c induced by valinomycin.
  • Reduced hepatotoxicity of acetaminophen in mice lacking inducible nitric oxide synthase: potential role of tumor necrosis factor-alpha and interleukin-10.
  • Presence of hydroxysteroid dehydrogenase type 10 in amyloid plaques (APs) of Hsiao's APP-Sw transgenic mouse brains, but absence in APs of Alzheimer's disease brains.
  • Defective thymocyte maturation by transgenic expression of a truncated form of the T lymphocyte adapter molecule and Fyn substrate, Sin.
  • Transgenic targeting with regulatory elements of the human CD34 gene.
  • Complete regression of established spontaneous mammary carcinoma and the therapeutic prevention of genetically programmed neoplastic transition by IL-12/pulse IL-2: induction of local T cell infiltration, Fas/Fas ligand gene expression, and mammary epithelial apoptosis.
  • Preclinical development of an adjuvant-free peptide vaccine with activity against CMV pp65 in HLA transgenic mice.
  • Distal elements are critical for human CD34 expression in vivo.
  • CCL25 mediates the localization of recently activated CD8alphabeta(+) lymphocytes to the small-intestinal mucosa.
  • Selection of potential therapeutics based on in vivo spatiotemporal transcription patterns of heme oxygenase-1.
  • A nonionic amphiphile agent promotes gene delivery in vivo to skeletal and cardiac muscles.
  • Characterization of the dCaMKII-GAL4 driver line whose expression is controlled by the Drosophila Ca2+/calmodulin-dependent protein kinase II promoter.
  • HLA-A2 1 restricted peptides from the HBx antigen induce specific CTL responses in vitro and in vivo.
  • Prenatal, but not postnatal, inhibition of fibroblast growth factor receptor signaling causes emphysema.
  • Two light-responsive elements of pea chloroplastic fructose-1,6-bisphosphatase gene involved in the red-light-specific gene expression in transgenic tobaccos.
  • Expression of hyperacetylated histone H4 during normal and impaired human spermatogenesis.
  • Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function.
  • Hepatitis B surface antigen (HBsAg) expression in plant cell culture: Kinetics of antigen accumulation in batch culture and its intracellular form.
  • Modeling the development of resistance by stalk-boring lepidopteran insects (Crambidae) in areas with transgenic corn and frequent insecticide use.
  • A viral suppressor of RNA silencing differentially regulates the accumulation of short interfering RNAs and micro-RNAs in tobacco.
  • Amyloid cored plaques in Tg2576 transgenic mice are characterized by giant plaques, slightly activated microglia, and the lack of paired helical filament-typed, dystrophic neurites.
  • Expression of the green fluorescent protein in the oligodendrocyte lineage: a transgenic mouse for developmental and physiological studies.
  • Rapid induction of uterine endometrial proliferative lesions in transgenic mice carrying a human prototype c-Ha-ras gene (rasH2 mice) given a single intraperitoneal injection of N-ethyl-N-nitrosourea.
  • Total lymphoid irradiation nonmyeloablative preconditioning enriches for IL-4-producing CD4+-TNK cells and skews differentiation of immunocompetent donor CD4+ cells.
  • Possible mechanism of gene transfer into early to mid-gestational mouse fetuses by tail vein injection.
  • Prevention of spontaneous mammary adenocarcinoma in HER-2/neu transgenic mice by foreign DNA.
  • The Nod factor-elicited annexin MtAnn1 is preferentially localised at the nuclear periphery in symbiotically activated root tissues of Medicago truncatula.
  • JNK activation is associated with intracellular beta-amyloid accumulation.
  • Assembly of tau in transgenic animals expressing P301L tau: alteration of phosphorylation and solubility.
  • Effects of liver-derived insulin-like growth factor I on bone metabolism in mice.
  • Effects of targeted overexpression of pleiotrophin on postnatal bone development.
  • Smad4 overexpression causes germ cell ablation and leydig cell hyperplasia in transgenic mice.
  • Borna disease virus accelerates inflammation and disease associated with transgenic expression of interleukin-12 in the central nervous system.
  • CD156 transgenic mice. Different responses between inflammatory types.
  • Reduced self-reactivity of an autoreactive T cell after activation with cross-reactive non-self-ligand.
  • Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein.
  • Plasma membrane-associated ROP10 small GTPase is a specific negative regulator of abscisic acid responses in Arabidopsis.
  • The Commelina yellow mottle virus promoter drives companion-cell-specific gene expression in multiple organs of transgenic tobacco.
  • Liposarcoma initiated by FUS/TLS-CHOP: the FUS/TLS domain plays a critical role in the pathogenesis of liposarcoma.
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  • Lung-specific expression of human mutant p53-273H is associated with a high frequency of lung adenocarcinoma in transgenic mice.
  • Antigen-driven murine CD4+ T lymphocyte proliferation and interleukin-2 production are diminished by dietary (n-3) polyunsaturated fatty acids.
  • The balance between donor T cell anergy and suppression versus lethal graft-versus-host disease is determined by host conditioning.
  • Generation of siRNAs by T-DNA sequences does not require active transcription or homology to sequences in the plant.
  • Expression of bacterial poly(3-hydroxybutyrate) synthesis genes in hairy roots of sugar beet (Beta vulgaris L.).
  • Targeted expression of IGF-1 transgene to skeletal muscle accelerates muscle and motor neuron regeneration.
  • Prostate targeting: PSP94 gene promoter/enhancer region directed prostate tissue-specific expression in a transgenic mouse prostate cancer model.
  • Spatial learning, exploration, anxiety, and motor coordination in female APP23 transgenic mice with the Swedish mutation.
  • Renal principal cell-specific expression of green fluorescent protein in transgenic mice.
  • Transgenic anti-CD4 monoclonal antibody secretion by mouse segmental pancreas allografts promotes long term survival.
  • Phenobarbital responsiveness conferred by the 5'-flanking region of the rat CYP2B2 gene in transgenic mice.
  • Starch content and yield increase as a result of altering adenylate pools in transgenic plants.
  • Disruption of corticocortical connections ameliorates amyloid burden in terminal fields in a transgenic model of Abeta amyloidosis.
  • Epithalon inhibits tumor growth and expression of HER-2/neu oncogene in breast tumors in transgenic mice characterized by accelerated aging.
  • Dendritic cell-tumor cell fusion and staphylococcal enterotoxin B treatment in a pancreatic tumor model.
  • Mutagenesis and DNA adduct formation in the mouse mammary gland exposed to 2-hydroxyamino-1-methyl-6-phenylimidazo-4,5-bpyridine in whole organ culture.
  • Heavy-chain only antibodies derived from dromedary are secreted and displayed by mouse B cells.
  • Familial amyotrophic lateral sclerosis with a point mutation (G37R) of the superoxide dismutase 1 gene: a clinicopathological study.
  • Field performance of transgenic tall fescue (Festuca arundinacea Schreb.) plants and their progenies.
  • A chemical-regulated inducible RNAi system in plants.
  • Novel targets and therapeutic strategies for type 2 diabetes.
  • Mutational analysis of the Arabidopsis nucleotide binding site-leucine-rich repeat resistance gene RPS2.
  • Initiation and synergistic fibrillization of tau and alpha-synuclein.
  • The mouse rasH2/BHT model as an in vivo rapid assay for lung carcinogens.
  • Vulnerability of allografts to rejection by MHC class II-restricted T-cell receptor transgenic mice.
  • MHC class II-expressing hepatocytes function as antigen-presenting cells and activate specific CD4 T lymphocyutes.
  • Novel transgenic rat for in vivo genotoxicity assays using 6-thioguanine and Spi- selection.
  • In vivo imaging of transcriptionally active estrogen receptors.
  • Mouse models with modified p53 sequences to study cancer and ageing.
  • Transformation of tobacco with a gene for the thermophilic acyl-lipid desaturase enhances the chilling tolerance of plants.
  • The pseudorabies virus immediate-early promoter directs neuronal tissue-specific expression in transgenic mice.
  • 125I-BMIPP and 18F-FDG uptake in a transgenic mouse model of stunned myocardium.
  • Enhanced selenium tolerance and accumulation in transgenic Arabidopsis expressing a mouse selenocysteine lyase.
  • Activating signal cointegrator 2 required for liver lipid metabolism mediated by liver X receptors in mice.
  • NMDA receptor blockade and hippocampal neuronal loss impair fear conditioning and position habit reversal in C57Bl/6 mice.
  • Mechanism of portal venous tolerant long-term MHC Class I L(d)-specific skin graft survival in transgenic 2CF1 mice.
  • Elevated expression of 12/15-lipoxygenase and cyclooxygenase-2 in a transgenic mouse model of prostate carcinoma.
  • Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes.
  • dHAND-Cre transgenic mice reveal specific potential functions of dHAND during craniofacial development.
  • Physiological coupling of donor and host cardiomyocytes after cellular transplantation.
  • Chemoprevention of mammary carcinogenesis in a transgenic mouse model by alpha-difluoromethylornithine (DFMO) in the diet is associated with decreased cyclin D1 activity.
  • Long-term accumulation of amyloid-beta in axons following brain trauma without persistent upregulation of amyloid precursor protein genes.
  • Regional brain cytochrome oxidase activity in beta-amyloid precursor protein transgenic mice with the Swedish mutation.
  • A versatile vector set for animal transgenesis.
  • Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis.
  • Inducible expression of keratinocyte growth factor (KGF) in mice inhibits lung epithelial cell death induced by hyperoxia.
  • Paracrine overexpression of IGFBP-4 in osteoblasts of transgenic mice decreases bone turnover and causes global growth retardation.
  • Cutting edge: the NK cell receptor 2B4 augments antigen-specific T cell cytotoxicity through CD48 ligation on neighboring T cells.
  • Experimental Assessment of the Role of Acetaldehyde in Alcoholic Cardiomyopathy.
  • Elevated SMAD1/beta-catenin molecular complexes and renal medullary cystic dysplasia in ALK3 transgenic mice.
  • Visuomotor behaviors in larval zebrafish after GFP-guided laser ablation of the optic tectum.
  • Late-onset obesity in mice transgenic for the human renin gene.
  • Biochemical and genetic association of plasma apolipoprotein A-II levels with familial combined hyperlipidemia.
  • Copper-zinc superoxide dismutase affects Akt activation after transient focal cerebral ischemia in mice.
  • Distribution of spontaneous CpG-associated G:C --> A:T mutations in the lacZ gene of Muta mice: effects of CpG methylation, the sequence context of CpG sites, and severity of mutations on the activity of the lacZ gene product.
  • Expression of rotavirus capsid protein VP6 in transgenic potato and its oral immunogenicity in mice.
  • Improved in planta expression of the human islet autoantigen glutamic acid decarboxylase (GAD65).
  • Relationships between cell division, expression of growth factors and microcirculation in the thyroids of Tg-A2aR transgenic mice and patients with Graves' disease.
  • PNPase activity determines the efficiency of mRNA 3'-end processing, the degradation of tRNA and the extent of polyadenylation in chloroplasts.
  • Normal cognitive behavior in two distinct congenic lines of transgenic mice hyperexpressing mutant APP SWE.
  • Lac z Histochemistry and immunohistochemistry reveal ephrin-B ligand expression in the inner ear.
  • The Arabidopsis genes RPW8.1 and RPW8.2 confer induced resistance to powdery mildew diseases in tobacco.
  • Prostate hyperplasia in a transgenic mouse with prostate-specific expression of prolactin.
  • Shortened life span, bradycardia, and hypotension in mice with targeted expression of an Igf2 transgene in smooth muscle cells.
  • Genetic modification removes an immunodominant allergen from soybean.
  • Expression of expanded repeat androgen receptor produces neurologic disease in transgenic mice.
  • Tissue-culture surfaces with mixtures of aminated and fluorinated functional groFedex. Part 1. Synthesis and characterization.
  • Trehalose 6-phosphate is indispensable for carbohydrate utilization and growth in Arabidopsis thaliana.
  • Myelination and motor coordination are increased in transferrin transgenic mice.
  • Role of superoxide in poly(ADP-ribose) polymerase upregulation after transient cerebral ischemia.
  • Myeloid cell expansion elicited by the progression of spontaneous mammary carcinomas in c-erbB-2 transgenic BALB/c mice suppresses immune reactivity.
  • Suppression of Muscle Hypercontraction by Mutations in the Myosin Heavy Chain Gene of Drosophila melanogaster.
  • A role for dendritic cells in the priming of antigen-specific CD4(+) and CD8(+) T lymphocytes by immune-stimulating complexes in vivo.
  • Antigenic drift as a mechanism for tumor evasion of destruction by cytolytic T lymphocytes.
  • Inhibition of cAMP response element-binding protein or dynorphin in the nucleus accumbens produces an antidepressant-like effect.
  • The control of apoptosis in lymphocyte selection.
  • Chronic inborn erythrocytosis leads to cardiac dysfunction and premature death in mice overexpressing erythropoietin.
  • A novel HIV-1 transgenic rat model of childhood HIV-1-associated nephropathy.
  • Hyperkeratosis and leukocytosis in transgenic mice carrying MHC class I chain-related gene B (MICB).
  • Bioluminescent detection of endotoxin effects on HIV-1 LTR-driven transcription in vivo.
  • Leuprorelin rescues polyglutamine-dependent phenotypes in a transgenic mouse model of spinal and bulbar muscular atrophy.
  • Low paraoxonase activity predicts coronary events in the Caerphilly Prospective Study.
  • Enhanced stress-tolerance of transgenic tobacco plants expressing a human dehydroascorbate reductase gene.
  • Temporal patterns of bone marrow cell differentiation following transplantation in doxorubicin-induced cardiomyopathy.
  • Thrombopoietin inside the pulmonary vessels in patients with and without pulmonary hypertension.
  • Clearance of apoptotic photoreceptors: elimination of apoptotic debris into the subretinal space and macrophage-mediated phagocytosis via phosphatidylserine receptor and integrin alphavbeta3.
  • IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: evidence for enhanced cutaneous immunity.
  • Enamel factors regulate expression of genes associated with cementoblasts.
  • IL-1 alpha, innate immunity, and skin carcinogenesis: the effect of constitutive expression of IL-1 alpha in epidermis on chemical carcinogenesis.
  • CIS1 Interacts with the Y532 of the Prolactin Receptor and Suppresses Prolactin-Dependent STAT5 Activation.
  • A Drosophila model to study the functions of TWIST orthologs in apoptosis and proliferation.
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  • Quantification of antioxidant activity in brain tissue homogenates using the 'total equivalent antioxidant capacity'.
  • Role of dual-site phospholamban phosphorylation in the stunned heart: insights from phospholamban site-specific mutants.
  • Transmembrane sema4E guides branchiomotor axons to their targets in zebrafish.
  • Mutation analysis of vinyl carbamate or urethane induced lung tumors in rasH2 transgenic mice.
  • Glucose metabolism and energy homeostasis in mouse hearts overexpressing dominant negative alpha2 subunit of AMP-activated protein kinase.
  • DNA repair investigations using siRNA.
  • Effects of dietary calcium on adipocyte lipid metabolism and body weight regulation in energy-restricted aP2-agouti transgenic mice.
  • Msx1 is a regulator of bone formation during development and postnatal growth: in vivo investigations in a transgenic mouse model.
  • Two strains of cabbage seed weevil (Coleoptera: Curculionidae) exhibit differential susceptibility to a transgenic oilseed rape expressing oryzacystatin I.
  • Effects of artificial diet containing GNA and GNA-expressing potatoes on the development of the aphid parasitoid Aphidius ervi Haliday (Hymenoptera: Aphidiidae).
  • Resistance to green leafhopper (Nephotettix virescens) and brown planthopper (Nilaparvata lugens) in transgenic rice expressing snowdrop lectin (Galanthus nivalis agglutinin; GNA).
  • Ecdysteroid titers in mated and unmated Drosophila melanogaster females.
  • Reactive astrocytes express cAMP-response-element-binding protein (CREB) binding protein (CBP) in the central nervous system of transgenic mice expressing a human Cu/Zn superoxide dismutase mutation.
  • Safety assessment of recombinant green fluorescent protein orally administered to weaned rats.
  • Engineered IGF-I expression induces glandular enlargement in the murine prostate.
  • Sodium-Inorganic Phosphate Cotransporter NaPi-IIb in the Epididymis and its Potential Role in Male Fertility Studied in a Transgenic Mouse Model.
  • The in vivo but not the in vitro am3 revertant frequencies increase linearly with increased ethylnitrosourea doses in spleen of mice transgenic for phiX174 am3, cs70 using the single burst assay.
  • Growth arrest of individual senile plaques in a model of Alzheimer's disease observed by in vivo multiphoton microscopy.
  • Tryptamine-induced resistance in tryptophan decarboxylase transgenic poplar and tobacco plants against their specific herbivores.
  • Sporamin-mediated resistance to beet cyst nematodes (Heterodera schachtii Schm.) is dependent on trypsin inhibitory activity in sugar beet (Beta vulgaris L.) hairy roots.
  • Transgenic overexpression of the Ca2+-binding protein S100A1 in the heart leads to increased in vivo myocardial contractile performance.
  • Mechanism of IL-12 mediated alterations in tumour blood vessel morphology: analysis using whole-tissue mounts.
  • Th2 cells shape the differentiation of developing T cell responses during interactions with dendritic cells in vivo.
  • Sexy transgenes: the impact of gene transfer and gene inactivation technologies on the understanding of mammalian sex determination.
  • Analysis of trans-silencing interactions using transcriptional silencers of varying strength and targets with and without flanking nuclear matrix attachment regions.
  • Expression of the bovine growth hormone alters the root morphology in transgenic tobacco plants.
  • Sensitive Flow Cytometric Analysis Reveals a Novel Type of Parent-of-Origin Effect in the Mouse Genome.
  • Vertebrate caudal gene expression gradients investigated by use of chick cdx-A/lacZ and mouse cdx-1/lacZ reporters in transgenic mouse embryos: evidence for an intron enhancer.
  • Functionally distinct, sequence-specific replicator and origin elements are required for Drosophila chorion gene amplification.
  • Preliminary report on the apparent breaking of resistance of a transgenic plum by chip bud inoculation of plum pox virus PPV-S.
  • Development of rhabdomyosarcoma in HER-2/neu transgenic p53 mutant mice.
  • The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse.
  • Low glutelin content1: a dominant mutation that suppresses the glutelin multigene family via RNA silencing in rice.
  • Down-regulation of the AtCCR1 gene in Arabidopsis thaliana: effects on phenotype, lignins and cell wall degradability.
  • Molecular targeting of Alzheimer's amyloid plaques for contrast-enhanced magnetic resonance imaging.
  • Family 19 chitinase of Streptomyces griseus HUT6037 increases plant resistance to the fungal disease.
  • Creatine therapy provides neuroprotection after onset of clinical symptoms in Huntington's disease transgenic mice.
  • Dominant repression of target genes by chimeric repressors that include the EAR motif, a repression domain, in Arabidopsis.
  • Degeneration of beta-amyloid-associated cholinergic structures in transgenic APP SW mice.
  • Germ-line transgenesis of the Tc1/mariner superfamily transposon Minos in Ciona intestinalis.
  • Peroxynitrite plays a role in methamphetamine-induced dopaminergic neurotoxicity: evidence from mice lacking neuronal nitric oxide synthase gene or overexpressing copper-zinc superoxide dismutase.
  • Gene silencing in transgenic soybean plants transformed via particle bombardment.
  • Characterisation of the expression of a novel constitutive maize promoter in transgenic wheat and maize.
  • Characterization of grapefruit plants (Citrus paradisi Macf.) transformed with citrus tristeza closterovirus genes.
  • Agrobacterium-mediated transformation of niger Guizotia abyssinica (L. f.) Cass. using seedling explants.
  • Assembly of cholera toxin B subunit full-length rotavirus NSP4 fusion protein oligomers in transgenic potato.
  • Isolation and characterization of the human CP49 gene promoter.
  • Optimization of isolation and functional characterization of primary murine aortic endothelial cells.
  • Characterization and mRNA expression in an unusual odontogenic lesion in a patient with tricho-dento-osseous syndrome.
  • In vivo gene transfer of Kv1.5 normalizes action potential duration and shortens QT interval in mice with long QT phenotype.
  • Expression of the chemokine IP-10 correlates with the accumulation of hepatic IFN-gamma and IL-18 mRNA in chronic hepatitis C but not in hepatitis B.
  • Downregulation of caffeic acid 3-O-methyltransferase and caffeoyl CoA 3-O-methyltransferase in transgenic alfalfa. impacts on lignin structure and implications for the biosynthesis of G and S lignin.
  • Suppression of fructokinase encoded by LeFRK2 in tomato stem inhibits growth and causes wilting of young leaves.
  • Overexpression of rat heat shock protein 70 is associated with reduction of early mitochondrial cytochrome C release and subsequent DNA fragmentation after permanent focal ischemia.
  • Hypothalamic orexin neurons regulate arousal according to energy balance in mice.
  • Netrins and DCC in the guidance of migrating neural crest-derived cells in the developing bowel and pancreas.
  • Inhibition of dystroglycan cleavage causes muscular dystrophy in transgenic mice.
  • A comparative phylogenetic analysis of full-length mariner elements isolated from the Indian tasar silkmoth, Antheraea mylitta (Lepidoptera: saturniidae).
  • Alterations in slow-twitch muscle phenotype in transgenic mice overexpressing the Ca2+ buffering protein parvalbumin.
  • Membrane targeting of rab GTPases is influenced by the prenylation motif.
  • Two types of plastid ftsZ genes in the liverwort Marchantia polymorpha.
  • Long-Term High-Level Reconstitution of NADPH Oxidase Activity in Murine X-Linked Chronic Granulomatous Disease Using a Bicistronic Vector Expressing gp91(phox) and a DeltaLNGFR Cell Surface Marker.
  • Targeted inactivation of Galpha(i) does not alter cardiac function or beta-adrenergic sensitivity.
  • The non-cyclooxygenase targets of non-steroidal anti-inflammatory drugs, lipoxygenases, peroxisome proliferator-activated receptor, inhibitor of kappa B kinase, and NF kappa B, do not reduce amyloid beta 42 production.
  • A resource of mapped dissociation launch pads for targeted insertional mutagenesis in the Arabidopsis genome.
  • Overexpression of the ASN1 gene enhances nitrogen status in seeds of Arabidopsis.
  • A role for the GCC-box in jasmonate-mediated activation of the PDF1.2 gene of Arabidopsis.
  • Transgenic overexpression of the oncofetal RNA binding protein KOC leads to remodeling of the exocrine pancreas.
  • Intramuscular injection of AAV-GDNF results in sustained expression of transgenic GDNF, and its delivery to spinal motoneurons by retrograde transport.
  • Map-based cloning of leaf rust resistance gene Lr21 from the large and polyploid genome of bread wheat.
  • Transforming growth factor beta signaling impairs Neu-induced mammary tumorigenesis while promoting pulmonary metastasis.
  • Ectopic synaptogenesis during retinal degeneration in the royal college of surgeons rat.
  • Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy.
  • Expression, purification, and characterization of human hemoglobins Gower-1 (zeta(2)epsilon(2)), Gower-2 (alpha(2)epsilon(2)), and Portland-2 (zeta(2)beta(2)) assembled in complex transgenic-knockout mice.
  • Inactivated parapoxvirus ovis (Orf virus) has antiviral activity against hepatitis B virus and herpes simplex virus.
  • Cholinergic neuropathology in a mouse model of Alzheimer's disease.
  • A study on introduction of chitinase gene and beta-1,3-glucanase gene into restorer line of dian-type hybrid rice (Oryza sativa L.) and enhanced resistance to blast (Magnaporthe grisea)
  • Expression of the C. elegans labial orthologue ceh-13 during male tail morphogenesis.
  • Transgenesis and neuroendocrine physiology: a transgenic rat model expressing growth hormone in vasopressin neurones.
  • Transgenic mouse models of human CYP3A4 gene regulation.
  • Filamentous tau in oligodendrocytes and astrocytes of transgenic mice expressing the human tau isoform with the P301L mutation.
  • Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice.
  • Validating the hen as a bioreactor for the production of exogenous proteins in egg white.
  • Bone malformations in interleukin-18 transgenic mice.
  • In vivo calcium imaging of brain activity in Drosophila by transgenic cameleon expression.
  • Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways.
  • Functional analysis of PKD1 transgenic lines reveals a direct role for polycystin-1 in mediating cell-cell adhesion.
  • Transgenic mouse models of hepatitis B virus-associated hepatocellular carcinoma.
  • A novel co-delivery system consisting of a Tomato bushy stunt virus and a defective interfering RNA for studying gene silencing.
  • Construction of recombinant pEGFP/hTRT plasmid
  • Dextran sulfate sodium-induced inflammation is enhanced by intestinal epithelial cell chemokine expression in mice.
  • Practical considerations of recombinant adeno-associated virus-mediated gene transfer for treatment of retinal degenerations.
  • A plant cyclin B2 is degraded early in mitosis and its ectopic expression shortens G2-phase and alleviates the DNA-damage checkpoint.
  • Conjugal transfer of plasmid pTF-FC2 from Agrobacterium to plant cells in the absence of T-DNA borders.
  • A Link between circadian-controlled bHLH factors and the APRR1/TOC1 quintet in Arabidopsis thaliana.
  • Dendritic cells are sufficient to cross-present self-antigens to CD8 T cells in vivo.
  • LAF1 ubiquitination by COP1 controls photomorphogenesis and is stimulated by SPA1.
  • Expression of hepatitis B virus X protein in transgenic mice.
  • Peripherin is not a contributing factor to motor neuron disease in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase.
  • Direct cell-cell interaction of cardiomyocytes is key for bone marrow stromal cells to go into cardiac lineage in vitro.
  • Current knowledge of gene flow in plants: implications for transgene flow.
  • Generation and functional characterization of a clonal murine periportal Kupffer cell line from H-2Kb -tsA58 mice.
  • Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice.
  • Secretion and accumulation of Abeta by brain vascular smooth muscle cells from AbetaPP-Swedish transgenic mice.
  • Enhanced free radical generation of FALSs-associated Cu,Zn-SOD mutants.
  • The Runx1 transcription factor inhibits the differentiation of naive CD4+ T cells into the Th2 lineage by repressing GATA3 expression.
  • Role of the complementarity-determining region 3 (CDR3) of the TCR-beta chains associated with the V alpha 14 semi-invariant TCR alpha-chain in the selection of CD4+ NK T Cells.
  • Restricted clonal expression of IL-2 by naive T cells reflects differential dynamic interactions with dendritic cells.
  • Horticultural characterization of Angelonia salicariifolia plants transformed with wild-type strains of Agrobacterium rhizogenes.
  • An efficient protocol for shoot regeneration and genetic transformation of pigeonpea Cajanus cajan (L) Millsp using leaf explants.
  • Differentiated thick ascending limb (TAL) cultured cells derived from SV40 transgenic mice express functional apical NHE2 isoform: effect of nitric oxide.
  • Transgenic animal models for type 1 diabetes: linking a tetracycline-inducible promoter with a virus-inducible mouse model.
  • Epidermal growth factor inhibition of c-Myc-mediated apoptosis through Akt and Erk involves Bcl-xL upregulation in mammary epithelial cells.
  • In vivo study of the GC90/IRIV vaccine for immune response and autoimmunity into a novel humanised transgenic mouse.
  • Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice.
  • The use of genetically altered mice for breast cancer prevention studies.
  • Birth of germline chimeras by transfer of chicken embryonic germ (EG) cells into recipient embryos.
  • NF-kappa B/Rel participation in the lymphokine-dependent proliferation of T lymphoid cells.
  • Regulatory transcription factors controlling function and differentiation of human trophoblast--a review.
  • Dissociation between neurodegeneration and caspase-11-mediated activation of caspase-1 and caspase-3 in a mouse model of amyotrophic lateral sclerosis.
  • Pre-clinical applications of transgenic mouse mammary cancer models.
  • What can rodent models tell us about cognitive decline in Alzheimer's disease?
  • United States Department of Agriculture-Agricultural Research Service: advances in the molecular genetic analysis of insects and their application to pest management.
  • Plasminogen activator/plasmin system: a major player in wound healing?
  • The conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule.
  • T cell antagonism is functionally uncoupled from the 21- and 23-kDa tyrosine-phosphorylated TCR zeta subunits.
  • Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice.
  • Developmental control of foraging and social behavior by the Drosophila neuropeptide Y-like system.
  • A critical role for CD2 in both thymic selection events and mature T cell function.
  • Characteristics of GABAergic neurons in the superficial superior colliculus in mice.
  • Expansion of natural killer cells in mice transgenic for IgM antibody to ganglioside GD2: demonstration of prolonged survival after challenge with syngeneic tumor cells.
  • Effects of GNA transgenic sugarcane on life history parameters of Parallorhogas pyralophagus (Marsh) (Hymenoptera: Braconidae), a parasitoid of Mexican rice borer.
  • Development, survival and fitness performance of Helicoverpa zea (Lepidoptera: Noctuidae) in MON810 Bt field corn.
  • The 5' terminal oligopyrimidine tract of human elongation factor 1A-1 gene functions as a transcriptional initiator and produces a variable number of Us at the transcriptional level.
  • The M domain of atToc159 plays an essential role in the import of proteins into chloroplasts and chloroplast biogenesis.
  • Metastasis of transgenic breast cancer in plasminogen activator inhibitor-1 gene-deficient mice.
  • Genetically engineered stem rust resistance in barley using the Rpg1 gene.
  • Antisense Bcl-xl down-regulation switches the response to topoisomerase I inhibition from senescence to apoptosis in colorectal cancer cells, enhancing global cytotoxicity.
  • Ectopic B-Raf expression enhances extracellular signal-regulated kinase (ERK) Signaling in T cells and prevents antigen presenting cell-induced anergy.
  • IL-13 overexpression predisposes to anaphylaxis following antigen sensitization.
  • Apparent trans-chromosomal antibody class switch in mice bearing an Igh(a) mu-chain transgene on an Igh(b) genetic background.
  • The Lotus japonicus ndx gene family is involved in nodule function and maintenance.
  • Activation tagging of a dominant gibberellin catabolism gene (GA 2-oxidase) from poplar that regulates tree stature.
  • Interacting transcription factors from the three-amino acid loop extension superclass regulate tuber formation.
  • Biochemical and molecular characterization of a novel UDP-glucose:anthocyanin 3'-O-glucosyltransferase, a key enzyme for blue anthocyanin biosynthesis, from gentian.
  • Transcriptional profiles of latent human immunodeficiency virus in infected individuals: effects of Tat on the host and reservoir.
  • Mouse models for telomere and telomerase biology.
  • Using a gene-switch transgenic approach to dissect distinct roles of MAP kinases in heart failure.
  • Immunization in tumor prevention.
  • Global identification of target genes regulated by APETALA3 and PISTILLATA floral homeotic gene action.
  • ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomes.
  • Determinants of human apolipoprotein a secretion from mouse hepatocyte cultures.
  • PERK eIF2alpha kinase regulates neonatal growth by controlling the expression of circulating insulin-like growth factor-I derived from the liver.
  • Differential Myocardial Gene Expression in the Development and Rescue of Murine Heart Failure.
  • Basic processes in phytoremediation and some applications to air pollution control.
  • Cholesteryl ester transfer protein expression is downregulated in hyperinsulinemic transgenic mice.
  • A Transgene and Its Expression Profile are Stably Transmitted to Offspring in Transgenic Medaka Generated by the Particle Gun Method.
  • The protection afforded by ischemic preconditioning is not mediated by effects on cell-to-cell electrical coupling during myocardial ischemia-reperfusion.
  • Attenuated signaling by a phosphotyrosine-null Epo receptor form in primary erythroid progenitor cells.
  • Huntington's disease: prospects for neuroprotective therapy 10 years after the discovery of the causative genetic mutation.
  • Lineage-specific overexpression of the P2Y1 receptor induces platelet hyper-reactivity in transgenic mice.
  • Role of nNOS in regulation of renal function in hypertensive Ren-2 transgenic rats.
  • Metallothionein expression protects against carbon tetrachloride-induced hepatotoxicity, but overexpression and dietary zinc supplementation provide no further protection in metallothionein transgenic and knockout mice.
  • Metaphase FISHing of transgenic mice recommended: FISH and SKY define BAC-mediated balanced translocation.
  • Cerebral arteriolar structure in mice overexpressing human renin and angiotensinogen.
  • Antizyme overexpression in transgenic mice reduces cell proliferation, increases apoptosis, and reduces N-nitrosomethylbenzylamine-induced forestomach carcinogenesis.
  • Increased thrombosis after arterial injury in human C-reactive protein-transgenic mice.
  • Chronic exposure to low levels of antigen in the periphery causes reversible functional impairment correlating with changes in CD5 levels in monoclonal CD8 T cells.
  • HER-2 DNA and protein vaccines containing potent Th cell epitopes induce distinct protective and therapeutic antitumor responses in HER-2 transgenic mice.
  • Modification of in vivo and in vitro T- and B-cell-mediated immune responses by the Pseudomonas aeruginosa quorum-sensing molecule N-(3-oxododecanoyl)-L-homoserine lactone.
  • Use of the tetracycline system for inducible protein synthesis in the kidney.
  • Neuron-specific activation of murine cytomegalovirus early gene e1 promoter in transgenic mice.
  • Immunization against luteinizing hormone-releasing hormone fusion proteins does not decrease prostate cancer in the transgenic adenocarcinoma mouse prostate model.
  • Cloning of an Arabidopsis Patatin-Like Gene, STURDY, by Activation T-DNA Tagging.
  • Junctin and calsequestrin overexpression in cardiac muscle: the role of junctin and the synthetic and delivery pathways for the two proteins.
  • Prolactin induces ERalpha-positive and ERalpha-negative mammary cancer in transgenic mice.
  • The use of the PMI/mannose selection system to recover transgenic sweet orange plants ( Citrus sinensis L. Osbeck).
  • An investigation of the distribution of antigen fed in tolerogenic or immunogenic forms.
  • Effects of altered gene order or orientation of the locus control region on human beta-globin gene expression in mice.
  • Convulxin binds to native, human glycoprotein Ibalpha (GPIbalpha ).
  • Therapeutic limitations in tumor-specific CD8+ memory T cell engraftment.
  • The kinase inhibitor PKC412 suppresses epiretinal membrane formation and retinal detachment in mice with proliferative retinopathies.
  • Pancreatic beta-cell lipotoxicity induced by overexpression of hormone-sensitive lipase.
  • Overexpression of human genes in Drosophila melanogaster by using GAL4 UAS system.
  • Molecular evolution of beta-glucuronidase in vitro: obtaining thermotolerant GUS gene
  • The effects of B7-dependent costimulation on T cell division and survival in vivo and in vitro are dependent on antigen concentration.
  • Does my mouse have Alzheimer's disease?
  • Transgene expression in the vegetative tissues of apple driven by the vascular-specific rolC and CoYMV promoters.
  • A sequential approach to risk assessment of transgenic plants expressing protease inhibitors: effects on nontarget herbivorous insects.
  • The Saccharomyces cerevisiae chitinase, encoded by the CTS1-2 gene, confers antifungal activity against Botrytis cinerea to transgenic tobacco.
  • Alterations in beta-amyloid production and deposition in brain regions of two transgenic models.
  • Expression of immunogenic S1 glycoprotein of infectious bronchitis virus in transgenic potatoes.
  • Improved reversal learning and altered fear conditioning in transgenic mice with regionally restricted p25 expression.
  • Induction of cre recombinase activity using modified androgen receptor ligand binding domains: a sensitive assay for ligand-receptor interactions.
  • Gossypol activates pancreatic polyamine catabolism in normal rats and induces acute pancreatitis in transgenic rats over-expressing spermidine/spermine N1-acetyltransferase.
  • Overexpression of a slit homologue impairs convergent extension of the mesoderm and causes cyclopia in embryonic zebrafish.
  • Development of transgenic fish for ornamental and bioreactor by strong expression of fluorescent proteins in the skeletal muscle.
  • The intrarenal renin-angiotensin system and diabetic nephropathy.
  • Cyclic AMP compartmentation due to increased cAMP-phosphodiesterase activity in transgenic mice with a cardiac-directed expression of the human adenylyl cyclase type 8 (AC8).
  • Involvement of the octadecanoid pathway and protein phosphorylation in fungal elicitor-induced expression of terpenoid indole alkaloid biosynthetic genes in catharanthus roseus
  • Neuronal overexpression of cyclooxygenase-2 increases cerebral infarction.
  • Ets Motifs Are Necessary for Endothelial Cell-Specific Expression of a 723-bp Tie-2 Promoter/Enhancer in Hprt Targeted Transgenic Mice.
  • Primary endothelial cells isolated from the yolk sac and para-aortic splanchnopleura (P-Sp) support the expansion of adult marrow stem cells in vitro.
  • 17Beta-estradiol treatment profoundly down-regulates gene expression in spinal cord tissue in mice protected from experimental autoimmune encephalomyelitis.
  • Electrophysiological studies on the hippocampus and prefrontal cortex assessing the effects of amyloidosis in amyloid precursor protein 23 transgenic mice.
  • Mouse mammary tumor virus c-rel transgenic mice develop mammary tumors.
  • Conditionally immortalized retinal capillary endothelial cell lines (TR-iBRB) expressing differentiated endothelial cell functions derived from a transgenic rat.
  • Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway.
  • ARC6 is a J-domain plastid division protein and an evolutionary descendant of the cyanobacterial cell division protein Ftn2.
  • Transgenic mice over-expressing substance P exhibit allodynia and hyperalgesia which are reversed by substance P and N-methyl-D-aspartate receptor antagonists.
  • Reduction in the endogenous arginine decarboxylase transcript levels in rice leads to depletion of the putrescine and spermidine pools with no concomitant changes in the expression of downstream genes in the polyamine biosynthetic pathway.
  • Argemone oil induced cellular damage in the reproductive tissues of transgenic Drosophila melanogaster: protective role of 70 kDa heat shock protein.
  • Predominant expression of human Agamma--in contrast with beta-globin gene in MEL cells transfected with the construct muLCRAgamma psibeta deltabeta.
  • In vitro and in vivo characterization of the minimal promoter region of the human thiamin transporter SLC19A2.
  • Generation of systemin signaling in tobacco by transformation with the tomato systemin receptor kinase gene.
  • ApoE4 impairs hippocampal plasticity isoform-specifically and blocks the environmental stimulation of synaptogenesis and memory.
  • Direct visualization of transplanted hematopoietic cell reconstitution in intact mouse organs indicates the presence of a niche.
  • RGS4 reduces contractile dysfunction and hypertrophic gene induction in Galpha q overexpressing mice.
  • Loss of responsiveness to chemotactic factors by deletion of the C-terminal protein interaction site of angiomotin.
  • T cell-intrinsic requirement for NF-kappaB induction in postdifferentiation IFN-gamma production and clonal expansion in a Th1 response.
  • Transgenic mice model of human hepatitis B virus x gene
  • Overexpression of a stress-inducible aldehyde dehydrogenase gene from Arabidopsis thaliana in transgenic plants improves stress tolerance.
  • Fetal Lungs of Tenascin-C-Deficient Mice Grow Well, but Branch Poorly in Organ Culture.
  • Immunopathogenesis of collagen arthritis.
  • Rapid inactivation of the maize transposable element En/Spm in Medicago truncatula.
  • VEGFR-2-specific ligand VEGF-E induces non-edematous hyper-vascularization in mice.
  • Gene silencing by expression of hairpin RNA in Lotus japonicus roots and root nodules.
  • Identification of an HLA-A*0201-restricted epitopic peptide from human dystrophin: application in duchenne muscular dystrophy gene therapy.
  • Chromosomal localization, expression pattern, and promoter analysis of the mouse gene encoding adipocyte-specific secretory protein Acrp30.
  • Reduced circulating insulin-like growth factor I levels delay the onset of chemically and genetically induced mammary tumors.
  • Sugar acts as a regulatory signal on the wound-inducible expression of SbHRGP3:: GUS in transgenic plants.
  • Human cone pigment expressed in transgenic mice yields altered vision.
  • Effect of hMSH6 cDNA expression on the phenotype of mismatch repair-deficient colon cancer cell line HCT15.
  • TGF-beta1 in liver fibrosis: an inducible transgenic mouse model to study liver fibrogenesis.
  • Overexpression of calcineurin in mouse causes sudden cardiac death associated with decreased density of K+ channels.
  • Placental glucose transporter expression is regulated by glucocorticoids.
  • Increased atherosclerosis in ApoE and LDL receptor gene knock-out mice as a result of human cholesteryl ester transfer protein transgene expression.
  • Homologous regulation of the gonadotropin-releasing hormone receptor gene is partially mediated by protein kinase C activation of an activator protein-1 element.
  • Listeriolysin O-dependent activation of endothelial cells during infection with Listeria monocytogenes: activation of NF-kappa B and upregulation of adhesion molecules and chemokines.
  • Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion.
  • A novel P0 glycoprotein transgene activates expression of lacZ in myelin-forming Schwann cells.
  • Renal expression of fibrotic matrix proteins and of transforming growth factor-beta (TGF-beta) isoforms in TGF-beta transgenic mice.
  • Effects of zinc ion concentration on growth, fat content and reproduction in oMT1a-oGH transgenic mice.
  • Association analysis between a Cys23Ser substitution polymorphism of the human 5-HT2c receptor gene and neuronal hyperexcitability.
  • A leucine-rich repeat protein of carrot that exhibits antifreeze activity.
  • Green fluorescent protein as a marker to investigate targeting of organellar RNA polymerases of higher plants in vivo.
  • Differential regulation of hypothalamic tuberoinfundibular dopamine neurones in two dwarf rat models with contrasting changes in pituitary prolactin.
  • Schwann cell hyperplasia and tumors in transgenic mice expressing a naturally occurring mutant NF2 protein.
  • Nicotine strongly activates dendritic cell-mediated adaptive immunity: potential role for progression of atherosclerotic lesions.
  • AUX1 regulates root gravitropism in Arabidopsis by facilitating auxin uptake within root apical tissues.
  • Analysis of the accumulation of mutants in Sabin attenuated polio vaccine viruses passaged in Vero cells.
  • Iron fortification of rice seed by the soybean ferritin gene.

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Concerned about losing hair? Hair loss and baldness is indeed a visible problem, and could be more than just the matter of change in appearance.
Saw palmetto berry is a widely known herbal supplement for hair loss problems. However, there are a number of great anecdotal herbs that people used for thousands of years stop
hair loss and start hair growth. Numerous anecdotal cases have demonstrated that this herbal formula based on Chinese herbs actually improves the age-related hair thinning and hair loss for a significant fraction of people who take it diligently. It is unknown how Hair Million herbs actually stop hair loss, and promote hair growth, No scientific research or placebo controlled clinical trials have been conducted. Nonetheless, a number of people agree that it works.
 
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